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APP Gene

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slug	entities-app
entity_type	gene
kg_node_id	None

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Linked Artifacts (72)

mentions🧫Plasma ATN biomarkers across AD continuum in Chilean cohort80%

mentions🧫Creation and validation of 3xAD-ChAT-Cre mouse model80%

mentions🧫Adoptive transfer of TCRAβ-Tregs in AD mouse model80%

mentions🔬CRISPR-based therapeutic approaches for neurodegenerative di75%

related🧫Plasma ATN biomarkers across AD continuum in Chilean cohort72%

related🧫Creation and validation of 3xAD-ChAT-Cre mouse model72%

related🧫Adoptive transfer of TCRAβ-Tregs in AD mouse model72%

mentions🧫Amyloid plaque load analysis in triple-mutant mouse brains70%

mentions🧫Comparison of free-text clinical reports vs Mini-ICF-APP str70%

mentions🧫Diosmin cognitive rescue in APP/PS1 mice70%

mentions🧫Behavioral assessment of APP/PSEN1/GD3S triple-mutant mice70%

mentions🧫Immunofluorescence analysis of cerebral microvascular densit70%

mentions🧫Chi3l1 deletion in APP/PS1 mouse model of Alzheimer's d70%

mentions🧫Transcriptomic profiling and differential expression analysi70%

mentions🧫AhR agonist effects on NEP in APP/PS1 mice70%

mentions🧫qPCR and western blot analysis of microvascular functional m70%

mentions🧫Anti-ASC antibody intracerebroventricular injection in APP/P70%

mentions🧫Proposed experiment from debate on Synaptic pruning by micro70%

mentions🧫s:** - Test MCU overexpression specifically in layer II neur70%

mentions🧫Proposed experiment from debate on Synaptic pruning by micro70%

mentions🧫Biomechanical Impact Profiles and Chronic Traumatic Encephal70%

mentions🧫Animal Model Comparison for Neurodegenerative Disease Therap70%

mentions🧫Down Syndrome Alzheimer's Disease: Mechanisms and Thera70%

mentions🧫Metal Ion Homeostasis Dysregulation in Alzheimer's Dise70%

mentions🧫Neural Stem Cell Therapy for Alzheimer's Disease70%

mentions🧫Prion Strain Diversity and Selective Vulnerability70%

mentions🧫Experiment Validation: In vitro ThT Assay70%

mentions🧫Microglial TREM2 Agonist In Vivo Efficacy70%

related🔬CRISPR-based therapeutic approaches for neurodegenerative di67%

mentions🧪Multi-Modal CRISPR Platform for Simultaneous Editing and Mon65%

related🧫Amyloid plaque load analysis in triple-mutant mouse brains63%

related🧫Comparison of free-text clinical reports vs Mini-ICF-APP str63%

related🧫Diosmin cognitive rescue in APP/PS1 mice63%

related🧫Behavioral assessment of APP/PSEN1/GD3S triple-mutant mice63%

related🧫Immunofluorescence analysis of cerebral microvascular densit63%

related🧫Chi3l1 deletion in APP/PS1 mouse model of Alzheimer's d63%

related🧫Transcriptomic profiling and differential expression analysi63%

related🧫AhR agonist effects on NEP in APP/PS1 mice63%

related🧫qPCR and western blot analysis of microvascular functional m63%

related🧫Anti-ASC antibody intracerebroventricular injection in APP/P63%

related🧫Proposed experiment from debate on Synaptic pruning by micro63%

related🧫s:** - Test MCU overexpression specifically in layer II neur63%

related🧫Proposed experiment from debate on Synaptic pruning by micro63%

related🧫Biomechanical Impact Profiles and Chronic Traumatic Encephal63%

related🧫Animal Model Comparison for Neurodegenerative Disease Therap63%

related🧫Down Syndrome Alzheimer's Disease: Mechanisms and Thera63%

related🧫Metal Ion Homeostasis Dysregulation in Alzheimer's Dise63%

related🧫Neural Stem Cell Therapy for Alzheimer's Disease63%

related🧫Prion Strain Diversity and Selective Vulnerability63%

related🧫Experiment Validation: In vitro ThT Assay63%

related🧫Microglial TREM2 Agonist In Vivo Efficacy63%

mentions🔬CRISPR-based therapeutic approaches for neurodegenerative di60%

related🧪Multi-Modal CRISPR Platform for Simultaneous Editing and Mon58%

related🔬CRISPR-based therapeutic approaches for neurodegenerative di54%

mentions🧪Palmitoylation-Targeted BACE1 Trafficking Disruptors50%

mentions🧪CYP46A1 Overexpression Gene Therapy50%

mentions🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th50%

related🔬What are the mechanisms underlying neuroinflammation resolut50%

related🔬Investigate how lipid raft composition (cholesterol metaboli50%

related🔬What are the mechanisms underlying neuroinflammation resolut50%

related🔬Investigate how lipid raft composition (cholesterol metaboli50%

mentions📖Alnylam Pharmaceuticals40%

mentions📖Arbor Biotechnologies40%

mentions📖Harvard University40%

mentions📖Peking University40%

mentions📖Peter St George-Hyslop40%

mentions📖Priavoid GmbH40%

mentions📖University of Toronto40%

mentions📖cureapp-inc40%

mentions📖gladstone40%

related🧪CYP46A1 Overexpression Gene Therapy40%

related🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th40%