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CR1 Gene — Complement Component 1q Receptor

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-genes-cr1
Related Entities
CR1
Metadata
sluggenes-cr1
entity_typegene
kg_node_idCR1
Linked Artifacts (96)
mentions🧪APOE Isoform Conversion Therapy70%
mentions🧪Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides70%
mentions🧪Age-Dependent Complement C4b Upregulation Drives Synaptic Vu65%
related🧪APOE Isoform Conversion Therapy63%
related🧪Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides63%
see_also📖SMAD2 Gene60%
see_also📖Alzheimer Indonesia60%
see_also📖Aging vs Neurodegeneration: Mechanistic Comparison Matrix60%
see_also📖ABCA7 (Redirect)60%
see_also📖ABCA1 - ATP-Binding Cassette Transporter A160%
see_also📖ABI3 Gene60%
see_also📖ACE Gene60%
see_also📖adam1760%
see_also📖CFH60%
see_also📖CR2 (Complement Receptor Type 2)60%
see_also📖EED60%
see_also📖MS4A6A Gene60%
see_also📖PILRB Gene60%
see_also📖RIN3 — Rho GTPase-Activating Protein 2560%
see_also📖C560%
see_also📖SIGLEC1 Gene60%
see_also📖C5 Protein60%
see_also📖gab260%
see_also📖MS4A4E Gene - Membrane-Spanning 4-Domains A4E60%
see_also📖NME8 Gene60%
see_also📖TOMM40 Gene60%
related🧪Age-Dependent Complement C4b Upregulation Drives Synaptic Vu58%
related🧪Blocking AGE-RAGE Signaling in Enteric Glia to Prevent Neuro55%
mentions🔬What are the mechanisms underlying senolytic therapy for age50%
mentions🧪SASP-Mediated Complement Cascade Amplification50%
mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer50%
mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones50%
mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction50%
mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy50%
mentions🧪Competitive APOE4 Domain Stabilization Peptides50%
mentions🧪APOE Isoform Expression Across Glial Subtypes50%
mentions🧪Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna50%
mentions🧪Complement C1QA Spatial Gradient in Cortical Layers50%
mentions🧪LRP1-Dependent Tau Uptake Disruption50%
mentions🧪TREM2 Conformational Stabilizers for Synaptic Discrimination50%
mentions🧪TREM2-mediated microglial tau clearance enhancement50%
mentions🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia50%
mentions🧪APOE4-Selective Lipid Nanoemulsion Therapy50%
mentions🧪APOE-TREM2 Interaction Modulation50%
mentions🧪TREM2-Mediated Selective Aggregate Clearance Pathway50%
mentions🧪TREM2-Dependent Microglial Senescence Transition50%
mentions🧪Complement C1q Mimetic Decoy Therapy50%
mentions🧪SASP-Mediated Complement Cascade Amplification50%
mentions🧪Complement C1q Subtype Switching50%
mentions🧪CYP46A1 Overexpression Gene Therapy50%
mentions🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th50%
mentions🧪Circadian Glymphatic Entrainment via Targeted Orexin Recepto50%
mentions🧪Magnetosonic-Triggered Transferrin Receptor Clustering50%
related🔬What are the mechanisms underlying blood-brain barrier trans50%
related🔬What are the mechanisms underlying neuroinflammation resolut50%
related🔬Investigate how lipid raft composition (cholesterol metaboli50%
related🔬What are the mechanisms underlying synaptic pruning by micro50%
related🔬What are the mechanisms underlying perivascular spaces and g50%
related🔬What are the mechanisms underlying 4r-tau strain-specific sp50%
related🔬What are the mechanisms underlying blood-brain barrier trans50%
related🔬What are the mechanisms underlying senolytic therapy for age50%
related🔬What are the mechanisms underlying neuroinflammation resolut50%
related🔬Investigate how lipid raft composition (cholesterol metaboli50%
related🔬What are the mechanisms underlying synaptic pruning by micro50%
related🔬What are the mechanisms underlying perivascular spaces and g50%
related🔬Analyze circuit-level changes in neurodegeneration using All50%
related🔬Comprehensive analysis of immune cell subtypes in neurodegen50%
related🔬Anti-amyloid antibodies (lecanemab, donanemab) have ~0.1% br50%
related🔬Microglia activate astrocytes via IL-1alpha/TNF/C1q, and rea50%
related🧪APOE Isoform Conversion Therapy50%
related🧪Selective HDAC3 Inhibition with Cognitive Enhancement50%
related🧪HDAC3-Selective Inhibition for Clock Reset50%
related🧪Oligodendrocyte White Matter Vulnerability50%
related🧪Piezoelectric Nanochannel BBB Disruption50%
related🔬What are the mechanisms underlying apoe4 structural biology 50%
related🔬SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas50%
mentions🔬Comprehensive analysis of immune cell subtypes in neurodegen40%
mentions🔬Microglia activate astrocytes via IL-1alpha/TNF/C1q, and rea40%
mentions🔬Analyze circuit-level changes in neurodegeneration using All40%
mentions🔬Anti-amyloid antibodies (lecanemab, donanemab) have ~0.1% br40%
related🧪Senescent Cell Mitochondrial DNA Release40%
related🧪SASP-Mediated Cholinergic Synapse Disruption40%
related🧪Senescence-Induced Lipid Peroxidation Spreading40%
related🧪SASP-Driven Aquaporin-4 Dysregulation40%
related🧪Senescence-Associated Myelin Lipid Remodeling40%
related🧪Senescence-Activated NAD+ Depletion Rescue40%
related🧪Complement C1q Mimetic Decoy Therapy40%
related🧪CYP46A1 Overexpression Gene Therapy40%
related🧪SASP-Mediated Complement Cascade Amplification40%
related🧪Complement C1q Subtype Switching40%
related🧪Circadian Glymphatic Entrainment via Targeted Orexin Recepto40%
related🧪Magnetosonic-Triggered Transferrin Receptor Clustering40%
related🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th40%
related🔬What are the mechanisms underlying senolytic therapy for age40%
related🔬Senolytics targeting p16/p21+ senescent astrocytes and micro40%
related🔬What are the mechanisms underlying 4r-tau strain-specific sp30%
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