gene

atg2a

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about atg2a: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

46Connections
0Hypotheses
0Analyses
3Outgoing
15Incoming

No summary available yet. View on Wiki →

🧬 Gene Info
Gene SymbolATG2A
Full NameAutophagy Related 2A
Chromosome11q13.2
Protein TypePeripheral Membrane Protein
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight206 kDa
UniProt ID[Q9BSB5](https://www.uniprot.org/uniprot/Q9BSB5)
GeneCardsATG2A
Human Protein AtlasATG2A
Associated DiseasesNeurodegeneration, neurodegeneration
InteractionsWIPI4
KG Connections3 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Wiki Pages (14)

Knowledge base pages for this entity

E2F4 Gene

gene · 2417 words

ATG9A Gene

gene · 1613 words

ATG9A Protein

protein · 1302 words

WIPI4 Gene

gene · 1196 words

WIPI1 Protein

protein · 995 words

Pathway Diagram

graph TD
    ATG2A["ATG2A"]
    ATG2A -->|"participates in"| autophagosome_lysosome_fusion["autophagosome-lysosome fusion"]
    ATG2A -->|"regulates"| phosphatidylethanolamine["phosphatidylethanolamine"]
    ATG2A -->|"activates"| Ms["Ms"]
    ATG2A -->|"activates"| Neurodegeneration["Neurodegeneration"]
    ATG2A -->|"activates"| Ferroptosis["Ferroptosis"]
    ATG2A -->|"activates"| Autophagy["Autophagy"]
    ATG2A -->|"activates"| WIPI4["WIPI4"]
    E2F4["E2F4"] -->|"regulates"| ATG2A
    WIPI4 -->|"interacts"| ATG2A
    NEURODEGENERATION["NEURODEGENERATION"] -->|"activates"| ATG2A
    FERROPTOSIS["FERROPTOSIS"] -->|"activates"| ATG2A
    WDR45["WDR45"] -->|"activates"| ATG2A
    MITOCHONDRIA["MITOCHONDRIA"] -->|"activates"| ATG2A
    AUTOPHAGY["AUTOPHAGY"] -->|"activates"| ATG2A

Outgoing (31)

TargetRelationTypeStr
MITOCHONDRIAactivatescell_type0.50
WIPI4activatesgene0.50
ENDOPLASMIC RETICULUMactivatesconcept0.50

Incoming (15)

SourceRelationTypeStr
E2F4regulatesprotein0.90
WIPI4regulatesprotein0.88
WIPI4interacts_withprotein0.80
YTHDF1associated_withprotein0.80
WIPI4activatesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found