concept

YTHDF1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about YTHDF1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

161Connections
0Hypotheses
0Analyses
50Outgoing
50Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameYTHDF1
Key Genes/ProteinsPIEZO2, ATG2A, ATG14
Related DiseasesNeurodegeneration, Aging, ALS, Cancer
Related Pathwaysm6A Modification

Wiki Pages (18)

Knowledge base pages for this entity

Epigenetic Mechanisms in Alzheimer's Disease

mechanism · 3425 words

Epigenetic Alterations in Alzheimer's Disease

pathway · 2868 words

RNA Stability and Decay

mechanism · 2809 words

Transcriptional Dysregulation in Neurodegeneration

mechanism · 2355 words

RNA Metabolism Dysfunction in Corticobasal Syndrome

mechanism · 1903 words

Pathway Diagram

graph TD
    YTHDF1["YTHDF1"]
    style YTHDF1 fill:#1a237e,stroke:#4fc3f7,stroke-width:3px
    YTHDF1 -->|"binds"| m6A_Modification["m6A Modification"]
    YTHDF1 -->|"binds"| PIEZO2([PIEZO2])
    YTHDF1 -->|"regulates"| Translation_Fidelity["Translation Fidelity"]
    YTHDF1 -->|"involved_in"| M6a_Epitranscriptomic_Modifica["M6a Epitranscriptomic Modification"]
    YTHDF1 -->|"mediates"| m6A_Epitranscriptomic_Modifica["m6A Epitranscriptomic Modification"]
    YTHDF1 -->|"contributes to"| Cancer["Cancer"]
    YTHDF1 -->|"interacts"| ALS["ALS"]
    YTHDF1 -->|"target for"| Als["Als"]
    YTHDF1 -->|"target for"| Aging["Aging"]
    GENES([GENES]) -->|"contributes to"| YTHDF1
    HNRNPA2B1([HNRNPA2B1]) -->|"interacts"| YTHDF1
    WTAP([WTAP]) -->|"contributes to"| YTHDF1
    RNA([RNA]) -->|"contributes to"| YTHDF1
    ALKBH5([ALKBH5]) -->|"contributes to"| YTHDF1
    AND([AND]) -->|"interacts"| YTHDF1
    FTO([FTO]) -->|"contributes to"| YTHDF1
    CLPP([CLPP]) -->|"target for"| YTHDF1
    LONP1([LONP1]) -->|"target for"| YTHDF1
    SNAP29([SNAP29]) -->|"target for"| YTHDF1

Outgoing (95)

TargetRelationTypeStr
m6A Modificationbindsprocess0.95
PIEZO2bindsgene0.95
PIEZO2regulatesgene0.95
N6-Methyladenosinebindscompound0.95
m6A Modificationassociated_withmechanism0.89

Incoming (66)

SourceRelationTypeStr
NEURODEGENERATIONassociated_withgene0.60
STX17associated_withgene0.60
WNTassociated_withgene0.60
SNAP29associated_withgene0.60
FUSassociated_withgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found