gene

atg4a

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about atg4a: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

18Connections
0Hypotheses
0Analyses
9Outgoing
9Incoming

No summary available yet. View on Wiki →

🧬 Gene Info
Gene SymbolATG4A
ChromosomeXq22.1
Protein TypeProtease
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionvarious tissues with high expression in:
Molecular Weight44 kDa
Amino Acids393 aa
Exons14
PathwaysmTOR, mtor
GeneCardsATG4A
Human Protein AtlasATG4A
Associated DiseasesNeurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Wiki Pages (10)

Knowledge base pages for this entity

ATG4D Gene

gene · 2054 words

ATG4B — Autophagy Related 4B Cysteine Peptidase

gene · 2013 words

ATG4C Gene

gene · 1845 words

ATG4B Protein — Autophagy Related 4B

protein · 1457 words

ATG4A Protein

protein · 1091 words

Pathway Diagram

flowchart TD
    N0["ATG4A"]
    N1["Ms"]
    N0 -->|"activates"| N1
    N2["MAP1LC3B2"]
    N0 -->|"causes"| N2
    N3["AUTOPHAGY"]
    N0 -->|"activates"| N3
    N4["Autophagy"]
    N0 -->|"activates"| N4
    N5["NEURODEGENERATIVE DISORDERS"]
    N5 -->|"activates"| N0
    N6["VIRAL INFECTIONS"]
    N6 -->|"activates"| N0
    N7["ATG7"]
    N7 -->|"causes"| N0
    N8["AND"]
    N8 -->|"causes"| N0
    N9["GENES"]
    N9 -->|"activates"| N0
    N10["TBK1"]
    N10 -->|"causes"| N0
    N11["neurodegeneration"]
    N0 -->|"implicated in"| N11

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
    class N1 disease
    class N2 gene
    class N3 gene
    class N4 pathway
    class N5 gene
    class N6 gene
    class N7 gene
    class N8 gene
    class N9 gene
    class N10 gene

Outgoing (9)

TargetRelationTypeStr
Msactivatesdisease0.65
ALSassociated_withdisease0.65
MAP1LC3B2causesgene0.60
ATG4Cassociated_withgene0.60
ATG4Bassociated_withgene0.60

Incoming (9)

SourceRelationTypeStr
ATG7causesgene0.60
TBK1causesgene0.60
ATG4Dassociated_withgene0.60
ATG4Bassociated_withgene0.60
NEURODEGENERATIVE DISORDERSactivatesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found