concept

BATF3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about BATF3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

37Connections

0Hypotheses

0Analyses

27Outgoing

10Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	BATF3
Key Genes/Proteins	TET2, MYC, AP-1
Related Diseases	Cancer, ALS, Tumor, Als

Pathway Diagram

graph TD
    BATF3["BATF3"]
    BATF3 -->|"activates"| CAR_T_Cell_Clonal_Expansion["CAR T Cell Clonal Expansion"]
    BATF3 -->|"activates"| CAR_T_CELL_EXPANSION["CAR T CELL EXPANSION"]
    BATF3 -->|"activates"| CAR_T_Cell_Expansion["CAR T Cell Expansion"]
    BATF3 -->|"activates"| MYC["MYC"]
    BATF3 -->|"activates"| Cancer["Cancer"]
    BATF3 -->|"activates"| ALS["ALS"]
    BATF3 -->|"activates"| Tumor["Tumor"]
    BATF3 -->|"activates"| Als["Als"]
    TET2["TET2"] -->|"regulates"| BATF3
    MYC -->|"expressed in"| BATF3
    CD8["CD8"] -->|"activates"| BATF3
    RIPK1["RIPK1"] -->|"activates"| BATF3
    RIPK3["RIPK3"] -->|"activates"| BATF3
    CANCER["CANCER"] -->|"activates"| BATF3
    JUN["JUN"] -->|"activates"| BATF3

Outgoing (27)

Target	Relation	Type	Str
CAR T Cell Clonal Expansion	activates	process	0.92
CAR T CELL EXPANSION	activates	entity	0.90
Car T Cell Clonal Expansion	promotes	process	0.90
CAR T cell proliferation	drives	process	0.90
CAR T Cell Expansion	activates	process	0.85
MYC	activates	gene	0.82
AP-1	interacts_with	protein	0.80
Cancer	activates	disease	0.65
ALS	activates	disease	0.65
Tumor	activates	disease	0.65
Als	activates	disease	0.65
TET2	activates	gene	0.60
AND	activates	gene	0.60
CANCER	activates	gene	0.60
Epigenetic	activates	pathway	0.60
JUN	activates	gene	0.60
RIPK3	activates	gene	0.60
Necroptosis	activates	pathway	0.60
Immune Response	activates	pathway	0.60
T Cell	activates	cell_type	0.60
CD8	activates	gene	0.60
Actin	activates	protein	0.60
App	activates	protein	0.60
T cells	expressed_in	cell_type	0.60
MYC	causes	gene	0.60
TET2	causes	gene	0.60
T Cell	expressed_in	cell_type	0.55

Incoming (10)

Source	Relation	Type	Str
TET2	protects_against	gene	0.95
TET2	regulates	gene	0.90
TET2	inhibits	gene	0.88
MYC	expressed_in	gene	0.60
CD8	activates	gene	0.60
RIPK1	activates	gene	0.60
RIPK3	activates	gene	0.60
CANCER	activates	gene	0.60
JUN	activates	gene	0.60
TET2	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found