Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about BEX2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | BEX2 |
| Key Genes/Proteins | CALCOCO2, NDP52, LC3B, DNA, APOPTOSIS |
| Related Diseases | crotonylation, Als, Carcinoma, Cancer, Tumor |
| Related Pathways | mitophagy, Apoptosis, Mitophagy |
Knowledge base pages for this entity
graph TD
BEX2["BEX2"]
BEX2 -->|"interacts"| CALCOCO2["CALCOCO2"]
BEX2 -->|"activates"| mitophagy["mitophagy"]
BEX2 -->|"interacts"| NDP52["NDP52"]
BEX2 -->|"regulates"| LC3B["LC3B"]
BEX2 -->|"inhibits"| APOPTOSIS["APOPTOSIS"]
BEX2 -->|"activates"| Cancer["Cancer"]
BEX2 -->|"regulates"| Tumor["Tumor"]
BEX2 -->|"interacts"| DNA["DNA"]
crotonylation["crotonylation"] -->|"modifies"| BEX2
APOPTOSIS -->|"activates"| BEX2
AND["AND"] -->|"activates"| BEX2
MITOPHAGY["MITOPHAGY"] -->|"activates"| BEX2
MITOCHONDRIA["MITOCHONDRIA"] -->|"expressed in"| BEX2
CANCER["CANCER"] -->|"activates"| BEX2| Target | Relation | Type | Str |
|---|---|---|---|
| CALCOCO2 | interacts_with | protein | 0.90 |
| mitophagy | activates | pathway | 0.90 |
| NDP52 | interacts_with | protein | 0.90 |
| LC3B | regulates | protein | 0.80 |
| Als | associated_with | disease | 0.65 |
| Carcinoma | associated_with | disease | 0.65 |
| Cancer | activates | disease | 0.65 |
| Tumor | regulates | disease | 0.65 |
| DNA | interacts_with | gene | 0.60 |
| NDP52 | activates | gene | 0.60 |
| LC3B | interacts_with | gene | 0.60 |
| Apoptosis | activates | pathway | 0.60 |
| Mitophagy | activates | pathway | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| crotonylation | modifies | phenotype | 0.90 |
| APOPTOSIS | activates | gene | 0.60 |
| AND | activates | gene | 0.60 |
| MITOPHAGY | activates | gene | 0.60 |
| MITOCHONDRIA | expressed_in | gene | 0.60 |
| CANCER | activates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||