CALCA

Understanding Entity Pages

This page aggregates everything SciDEX knows about CALCA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CALCA encodes calcitonin and α-CGRP, neuropeptides involved in pain transmission, neuroinflammation, vasodilation, and implicated in migraine, AD, and stroke.

View on Wiki →

graph TD
    CALCA["<b>CALCA</b>"]
    Ms{"Ms"}
    CALCA -->|"inhibits"| Ms
    BDNF["BDNF"]
    CALCA -->|"inhibits"| BDNF
    GENES["GENES"]
    CALCA -->|"associated with"| GENES
    IL18["IL18"]
    CALCA -->|"associated with"| IL18
    NR3C1["NR3C1"]
    CALCA -->|"inhibits"| NR3C1
    FKBP5["FKBP5"]
    CALCA -->|"inhibits"| FKBP5
    RAMP1["RAMP1"]
    CALCA -->|"associated with"| RAMP1
    CRH["CRH"]
    CALCA -->|"inhibits"| CRH
    IL18BP["IL18BP"]
    CALCA -->|"associated with"| IL18BP
    CRHR1["CRHR1"]
    CALCA -->|"inhibits"| CRHR1
    AND["AND"]
    CALCA -->|"associated with"| AND
    Amygdala["Amygdala"]
    CALCA -->|"expressed in"| Amygdala
    IL18 -->|"associated with"| CALCA
    RAMP1 -->|"associated with"| CALCA
    FKBP5 -->|"inhibits"| CALCA
    CRH -->|"inhibits"| CALCA
    CRHR1 -->|"inhibits"| CALCA
    NR3C1 -->|"inhibits"| CALCA
    BDNF -->|"inhibits"| CALCA
    IL18BP -->|"associated with"| CALCA
    GENES -->|"associated with"| CALCA
    style CALCA fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0