PRKCD

Understanding Entity Pages

This page aggregates everything SciDEX knows about PRKCD: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

PRKCD is a gene implicated in neurodegeneration research. Key relationships include: inhibits, therapeutic target, associated with. Associated with Als, Cancer, Ms. Connected to 52 entities in the SciDEX knowledge graph.

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graph TD
    PRKCD["<b>PRKCD</b>"]
    caspase_3["caspase-3"]
    PRKCD -->|"activates"| caspase_3
    DNA_fragmentation["DNA fragmentation"]
    PRKCD -->|"causes"| DNA_fragmentation
    APP["APP"]
    PRKCD -->|"associated with"| APP
    EGFR["EGFR"]
    PRKCD -->|"associated with"| EGFR
    MAPK1["MAPK1"]
    PRKCD -->|"associated with"| MAPK1
    ESR1["ESR1"]
    PRKCD -->|"associated with"| ESR1
    HSPA4["HSPA4"]
    PRKCD -->|"associated with"| HSPA4
    MAPK3["MAPK3"]
    PRKCD -->|"associated with"| MAPK3
    ABL1["ABL1"]
    PRKCD -->|"associated with"| ABL1
    JUN["JUN"]
    PRKCD -->|"associated with"| JUN
    GSK3B["GSK3B"]
    PRKCD -->|"associated with"| GSK3B
    Hifs(["Hifs"])
    PRKCD -->|"activates"| Hifs
    SQSTM1["SQSTM1"]
    SQSTM1 -->|"inhibits"| PRKCD
    MAP1LC3B["MAP1LC3B"]
    MAP1LC3B -->|"inhibits"| PRKCD
    GRID1["GRID1"]
    GRID1 -->|"inhibits"| PRKCD
    GLUD1["GLUD1"]
    GLUD1 -->|"inhibits"| PRKCD
    LAMP1["LAMP1"]
    LAMP1 -->|"expressed in"| PRKCD
    CBLN1["CBLN1"]
    CBLN1 -->|"inhibits"| PRKCD
    BECN1["BECN1"]
    BECN1 -->|"expressed in"| PRKCD
    style PRKCD fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0