Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CREB signaling: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| neurons | active_in | cell_type | 0.70 |
| unfolded protein response | crosstalk_with | pathway | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| CREB | participates_in | gene | 0.90 |
| BDNF | participates_in | gene | 0.60 |
| BDNF-TrkB signaling | crosstalk_with | pathway | 0.60 |
| CREB1 | participates_in | gene | 0.60 |
| ERK | participates_in | gene | 0.60 |
| Alzheimer's disease | involves | disease | 0.60 |
| ALS | participates_in | gene | 0.60 |
| ALS | involves | disease | 0.60 |
| frontotemporal dementia | involves | disease | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||