CREB1

Understanding Entity Pages

This page aggregates everything SciDEX knows about CREB1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CREB1 is a protein involved in neurodegeneration research. Key relationships include: activates, treats, interacts with. Associated with Aging, Als, Anxiety. Connected to 57 entities in the SciDEX knowledge graph.

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graph TD
    CREB1["<b>CREB1</b>"]
    TFEB["TFEB"]
    CREB1 -->|"activates"| TFEB
    PIEZO1["PIEZO1"]
    CREB1 -->|"regulates"| PIEZO1
    Als{"Als"}
    CREB1 -->|"regulates"| Als
    Ms{"Ms"}
    CREB1 -->|"contributes to"| Ms
    Schizophrenia{"Schizophrenia"}
    CREB1 -->|"activates"| Schizophrenia
    PPARGC1A["PPARGC1A"]
    CREB1 -->|"activates"| PPARGC1A
    AMPK["AMPK"]
    CREB1 -->|"activates"| AMPK
    EXERCISE["EXERCISE"]
    CREB1 -->|"activates"| EXERCISE
    Mapk(["Mapk"])
    CREB1 -->|"activates"| Mapk
    neurodegeneration["neurodegeneration"]
    CREB1 -->|"implicated in"| neurodegeneration
    TRIM27["TRIM27"]
    TRIM27 -->|"interacts with"| CREB1
    REST["REST"]
    REST -->|"activates"| CREB1
    P38["P38"]
    P38 -->|"activates"| CREB1
    EP300["EP300"]
    EP300 -->|"interacts with"| CREB1
    MET["MET"]
    MET -->|"expressed in"| CREB1
    CREBBP["CREBBP"]
    CREBBP -->|"activates"| CREB1
    style CREB1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0