Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CIRCADIAN RHYTHM DISRUPTION: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet. View on Wiki →
| Name | CIRCADIAN RHYTHM DISRUPTION |
Knowledge base pages for this entity
graph TD
CIRCADIAN_RHYTHM_DISRUPTION["CIRCADIAN RHYTHM DISRUPTION"]
CIRCADIAN_RHYTHM_DISRUPTION -->|"contributes to"| NEURODEGENERATION["NEURODEGENERATION"]
CIRCADIAN_RHYTHM_DISRUPTION -->|"contributes to"| NEUROINFLAMMATION["NEUROINFLAMMATION"]
CIRCADIAN_RHYTHM_DISRUPTION -->|"contributes to"| OXIDATIVE_STRESS["OXIDATIVE STRESS"]
CIRCADIAN_RHYTHM_DISRUPTION -->|"contributes to"| Tumor_Occurrence["Tumor Occurrence"]
CIRCADIAN_RHYTHM_DISRUPTION -->|"contributes to"| Tumor_Progression["Tumor Progression"]
CIRCADIAN_RHYTHM_DISRUPTION -->|"contributes to"| CANCER["CANCER"]
CIRCADIAN_RHYTHM_DISRUPTION -->|"contributes to"| Neurodegeneration["Neurodegeneration"]
CIRCADIAN_RHYTHM_DISRUPTION -->|"causes"| Sleep_Disruption["Sleep Disruption"]
Acute_Sleep_Deprivation["Acute Sleep Deprivation"] -->|"causes"| CIRCADIAN_RHYTHM_DISRUPTION
BMAL1["BMAL1"] -->|"involved_in"| CIRCADIAN_RHYTHM_DISRUPTION
CRY1["CRY1"] -->|"involved_in"| CIRCADIAN_RHYTHM_DISRUPTION
laparotomy["laparotomy"] -->|"causes"| CIRCADIAN_RHYTHM_DISRUPTION
MTNR1A["MTNR1A"] -->|"regulates"| CIRCADIAN_RHYTHM_DISRUPTION| Target | Relation | Type | Str |
|---|---|---|---|
| NEURODEGENERATION | contributes_to | entity | 0.90 |
| NEUROINFLAMMATION | contributes_to | entity | 0.90 |
| OXIDATIVE STRESS | contributes_to | entity | 0.90 |
| CANCER | contributes_to | entity | 0.87 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Acute Sleep Deprivation | causes | process | 0.95 |
| BMAL1 | involved_in | gene | 0.90 |
| CRY1 | involved_in | gene | 0.90 |
| CLOCK | involved_in | gene | 0.90 |
| laparotomy | causes | phenotype | 0.80 |
| Aging | causes | disease | 0.70 |
| Neurodegenerative Diseases | causes | disease | 0.70 |
| MTNR1A | regulates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-02 | 0 hypotheses
neurodegeneration | 2026-04-02 | 0 hypotheses
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||