gene

DGKQ

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DGKQ: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

23Connections
0Hypotheses
0Analyses
19Outgoing
4Incoming

Summary

Page for DGKQ

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🧬 Gene Info
Gene SymbolDGKQ
Full NameDiacylglycerol Kinase Theta
Chromosome19p13.3
Protein TypeKinase
FunctionDGKQ (Diacylglycerol Kinase Theta) is a member of the diacylglycerol kinase family that catalyzes the phosphorylation of diacylglycerol (DAG) to phosphatidic acid (PA), a critical lipid signaling reac
Primary Expressionthe brain, with high expression in the cortex, hippocampus, basal ganglia, and cerebellum
Subcellular Localizationthe cytoplasm and synaptic vesicles in neurons
PathwaysmTOR, mtor, mTOR signaling
UniProt ID[Q86XR1](https://www.uniprot.org/uniprot/Q86XR1)
Ensembl IDENSG00000145214
OMIM604017
GeneCardsDGKQ
Human Protein AtlasDGKQ
Associated DiseasesParkinson's disease
KG Connections23 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Wiki Pages (5)

Knowledge base pages for this entity

Canonical Page

DGKQ

gene · 673 words

sporadic-familial-pd-comparison

disease · 3585 words

Lipid Dysregulation in Neurodegeneration

mechanism · 2436 words

Parkinson's Disease Genetic Variants

disease · 1462 words

Genes

index · 271 words

Pathway Diagram

flowchart TD
    N0["DGKQ"]
    N1["Parkinson's disease"]
    N0 -->|"associated with"| N1
    N2["Als"]
    N0 -->|"expressed in"| N2
    N3["ALS"]
    N0 -->|"expressed in"| N3
    N4["GENES"]
    N0 -->|"expressed in"| N4
    N5["PDE4B"]
    N0 -->|"expressed in"| N5
    N6["BDNF"]
    N0 -->|"expressed in"| N6
    N7["MIR-155"]
    N0 -->|"expressed in"| N7
    N8["AND"]
    N0 -->|"expressed in"| N8
    N9["NTRK2"]
    N0 -->|"expressed in"| N9
    N10["MICRORNAS"]
    N0 -->|"expressed in"| N10
    N11["Bdnf"]
    N0 -->|"expressed in"| N11
    N12["Ras"]
    N0 -->|"expressed in"| N12
    N13["Fus"]
    N0 -->|"expressed in"| N13
    N10 -->|"expressed in"| N0

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 disease
    class N2 disease
    class N3 disease
    class N4 gene
    class N5 gene
    class N6 gene
    class N7 gene
    class N8 gene
    class N9 gene
    class N10 gene
    class N11 protein
    class N12 protein
    class N13 protein

Outgoing (19)

TargetRelationTypeStr
Parkinson's diseaseassociated_withdisease0.70
Alsexpressed_indisease0.65
ALSexpressed_indisease0.65
PDE4Bexpressed_ingene0.60
BDNFexpressed_ingene0.60

Incoming (4)

SourceRelationTypeStr
PDE4Bexpressed_ingene0.60
NTRK2expressed_ingene0.60
BDNFexpressed_ingene0.60
MICRORNASexpressed_ingene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found