concept

MIR-155

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MIR-155: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

95Connections

0Hypotheses

0Analyses

46Outgoing

41Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	MIR-155
Key Genes/Proteins	EGR1, AND, ALZHEIMER'S DISEASE, HNF4A, CCND1
Related Diseases	Als, Alzheimer, Aging, Neurodegeneration, ALS
Related Pathways	Phagocytosis

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    MIR_155["MIR-155"]
    MIR_155 -->|"promotes"| vascular_inflammation["vascular inflammation"]
    MIR_155 -->|"binds_to"| IRF2BP2["IRF2BP2"]
    MIR_155 -->|"promotes"| IL_6["IL-6"]
    MIR_155 -->|"expressed in"| Als["Als"]
    MIR_155 -->|"activates"| Alzheimer["Alzheimer"]
    MIR_155 -->|"activates"| Aging["Aging"]
    MIR_155 -->|"activates"| Neurodegeneration["Neurodegeneration"]
    MECP2["MECP2"] -->|"target for"| MIR_155
    MICRORNAS["MICRORNAS"] -->|"expressed in"| MIR_155
    CLEC7A["CLEC7A"] -->|"activates"| MIR_155
    AMYLOID["AMYLOID"] -->|"activates"| MIR_155
    ALZHEIMER["ALZHEIMER"] -->|"activates"| MIR_155
    RNA["RNA"] -->|"activates"| MIR_155
    MICROGLIA["MICROGLIA"] -->|"activates"| MIR_155
    PHAGOCYTOSIS["PHAGOCYTOSIS"] -->|"activates"| MIR_155

Outgoing (53)

Target	Relation	Type	Str
Neuroinflammation	upregulates	process	0.85
Als	expressed_in	disease	0.65
Alzheimer	activates	disease	0.65
Aging	activates	disease	0.65
Neurodegeneration	activates	disease	0.65
Alzheimer	regulates	disease	0.65
ALS	expressed_in	disease	0.65
ALS	associated_with	disease	0.65
Microglia	activates	cell_type	0.60
Phagocytosis	activates	pathway	0.60
EGR1	activates	gene	0.60
AND	activates	gene	0.60
ALZHEIMER'S DISEASE	regulates	gene	0.60
HNF4A	activates	gene	0.60
CCND1	activates	gene	0.60
GENES	activates	gene	0.60
MYC	activates	gene	0.60
YWHAZ	activates	gene	0.60
TXNIP	activates	gene	0.60
ALZHEIMER	regulates	gene	0.60
SOCS3	activates	gene	0.60
RELA	activates	gene	0.60
SPI1	activates	gene	0.60
TBP	activates	gene	0.60
Amyloid	regulates	pathway	0.60
AND	expressed_in	gene	0.60
MICRORNAS	expressed_in	gene	0.60
MECP2	expressed_in	gene	0.60
AND	associated_with	gene	0.60
NTRK2	expressed_in	gene	0.60
MICRORNAS	associated_with	gene	0.60
RNA	activates	gene	0.60
ALZHEIMER'S DISEASE	activates	gene	0.60
AMYLOID	activates	gene	0.60
TREM2	activates	gene	0.60
MICROGLIA	activates	gene	0.60
Amyloid	activates	pathway	0.60
MIRNAS	associated_with	gene	0.60
MECP2	therapeutic_target	gene	0.60
ALZHEIMER	activates	gene	0.60
CLEC7A	activates	gene	0.60
Rb	associated_with	protein	0.60
Ras	therapeutic_target	protein	0.60
Hippocampus	expressed_in	brain_region	0.55
Cerebellum	expressed_in	brain_region	0.55
Microglia	expressed_in	cell_type	0.55

Incoming (42)

Source	Relation	Type	Str
MECP2	therapeutic_target	gene	0.60
MICRORNAS	expressed_in	gene	0.60
MIRNAS	associated_with	gene	0.60
CLEC7A	activates	gene	0.60
AMYLOID	activates	gene	0.60
ALZHEIMER	activates	gene	0.60
RNA	activates	gene	0.60
MICROGLIA	activates	gene	0.60
PHAGOCYTOSIS	activates	gene	0.60
ALZHEIMER	regulates	gene	0.60
STAT1	activates	gene	0.60
MYH9	activates	gene	0.60
HUB GENES	regulates	gene	0.60
AMYLOID	regulates	gene	0.60
AXIN1	activates	gene	0.60
STAT3	activates	gene	0.60
MIRNAS	activates	gene	0.60
MICRORNAS	regulates	gene	0.60
RHEB	activates	gene	0.60
GENES	associated_with	gene	0.60
CREB1	expressed_in	gene	0.60
MEF2C	expressed_in	gene	0.60
GAIN	regulates	gene	0.60
DGKQ	expressed_in	gene	0.60
PDE4B	expressed_in	gene	0.60
BDNF	expressed_in	gene	0.60
NEURODEGENERATION	activates	gene	0.60
APOE	activates	gene	0.60
SPI1	activates	gene	0.60
SOCS3	activates	gene	0.60
ALZHEIMER'S DISEASE	regulates	gene	0.60
TBP	activates	gene	0.60
MYC	activates	gene	0.60
HNF4A	activates	gene	0.60
YWHAZ	activates	gene	0.60
RELA	activates	gene	0.60
AND	activates	gene	0.60
GENES	activates	gene	0.60
TXNIP	activates	gene	0.60
EGR1	activates	gene	0.60
CCND1	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

MIR-155

Understanding Entity Pages

Wiki Pages (20)

Epigenetic Dysregulation in Neurodegeneration

Epigenetic Alterations in Alzheimer's Disease

RNA Metabolism Dysregulation in Alzheimer's Disease

Liquid Biopsy Diagnostics for Corticobasal Syndrome

Liquid Biopsy Diagnostics for Corticobasal Syndrome

Microglial Senescence Pathway in Neurodegeneration

Transcriptional Regulation in Neurodegeneration

NF-κB Signaling Pathway in Neurodegeneration

TREM2→Microglial Dysfunction→Alzheimer's Disease Causal Chain

Neuroinflammation in Amyotrophic Lateral Sclerosis

Biomarker Rankings

Neuroinflammation in Parkinson's Disease

MS4A4A Gene — Membrane-Spanning 4-Domains A4A

NLRP3 Inflammasome Activation Pathway in Neurodegeneration

ALS RNA Metabolism and Proteostasis Failure

Epigenetic Changes in PSP

Neuroinflammation in Alzheimer's Disease

Chromatin Remodeling in Neurodegeneration