Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Cerebellum: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
graph TD
Cerebellum["Cerebellum"] -->|"associated"| Purkinje_Cell["Purkinje Cell"]
style Purkinje_Cell fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
THAP11["THAP11"] -->|"expressed in"| Cerebellum["Cerebellum"]
style THAP11 fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
C9orf72_Repeat_Expansion["C9orf72 Repeat Expansion"] -->|"expressed in"| Cerebellum["Cerebellum"]
style C9orf72_Repeat_Expansion fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
Purkinje_Cell_1["Purkinje Cell"] -->|"associated"| Cerebellum["Cerebellum"]
style Purkinje_Cell_1 fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
ATP["ATP"] -->|"expressed in"| Cerebellum["Cerebellum"]
style ATP fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
DRP1["DRP1"] -->|"expressed in"| Cerebellum["Cerebellum"]
style DRP1 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
style Cerebellum fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold| Target | Relation | Type | Str |
|---|---|---|---|
| Purkinje Cell | associated_with | entity | 0.70 |
| Purkinje Cell | interacts_with | entity | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| THAP11 | expressed_in | protein | 0.88 |
| C9orf72 Repeat Expansion | expressed_in | mechanism | 0.80 |
| Purkinje Cell | associated_with | entity | 0.70 |
| Purkinje Cell | inhibits | entity | 0.70 |
| Purkinje Cell | expressed_in | entity | 0.70 |
| Purkinje Cell | interacts_with | entity | 0.70 |
| Purkinje Cell | activates | entity | 0.70 |
| ATP | expressed_in | gene | 0.55 |
| DRP1 | expressed_in | gene | 0.55 |
| PRKAA1 | expressed_in | gene | 0.55 |
| JUN | expressed_in | gene | 0.55 |
| NRF1 | expressed_in | gene | 0.55 |
| OPA1 | expressed_in | gene | 0.55 |
| AMPK | expressed_in | gene | 0.55 |
| GENES | expressed_in | gene | 0.55 |
| DNM1L | expressed_in | gene | 0.55 |
| MFN1 | expressed_in | gene | 0.55 |
| SIRT1 | expressed_in | gene | 0.55 |
| PPARGC1A | expressed_in | gene | 0.55 |
| MITOCHONDRIAL DYSFUNCTION | expressed_in | gene | 0.55 |
| JAM2 | expressed_in | gene | 0.55 |
| XPR1 | expressed_in | gene | 0.55 |
| SLC20A2 | expressed_in | gene | 0.55 |
| PARKINSON'S DISEASE | expressed_in | gene | 0.55 |
| PARKINSON | expressed_in | gene | 0.55 |
| PDGFRB | expressed_in | gene | 0.55 |
| PDGFB | expressed_in | gene | 0.55 |
| VDR | expressed_in | gene | 0.55 |
| AND | expressed_in | gene | 0.55 |
| CMPK2 | expressed_in | gene | 0.55 |
| MYORG | expressed_in | gene | 0.55 |
| AQP4 | expressed_in | gene | 0.55 |
| MYELIN | expressed_in | gene | 0.55 |
| OLIGODENDROCYTE | expressed_in | gene | 0.55 |
| HEXANUCLEOTIDE REPEAT EXPANSIONS | expressed_in | gene | 0.55 |
| DEMENTIA | expressed_in | gene | 0.55 |
| DNA | expressed_in | gene | 0.55 |
| AMYOTROPHIC LATERAL SCLEROSIS | expressed_in | gene | 0.55 |
| TDP-43 | expressed_in | gene | 0.55 |
| GAIN | expressed_in | gene | 0.55 |
| RNA | expressed_in | gene | 0.55 |
| C9ORF72 | expressed_in | gene | 0.55 |
| NEURODEGENERATION | expressed_in | gene | 0.55 |
| MITOCHONDRIA | expressed_in | gene | 0.55 |
| MITOPHAGY | expressed_in | gene | 0.55 |
| APOPTOSIS | expressed_in | gene | 0.55 |
| ALZHEIMER | expressed_in | gene | 0.55 |
| APP | expressed_in | gene | 0.55 |
| SGMS1 | expressed_in | gene | 0.55 |
| ALZHEIMER'S DISEASE | expressed_in | gene | 0.55 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||