GAK

Understanding Entity Pages

This page aggregates everything SciDEX knows about GAK: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Cyclin G-associated kinase (GAK), a serine/threonine kinase involved in endocytosis, autophagy, and neurodegeneration

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graph TD
    GAK["<b>GAK</b>"]
    Parkinson{"Parkinson"}
    GAK -->|"associated with"| Parkinson
    Als{"Als"}
    GAK -->|"associated with"| Als
    Ms{"Ms"}
    GAK -->|"associated with"| Ms
    SYNJ1["SYNJ1"]
    GAK -->|"associated with"| SYNJ1
    AUTOPHAGY["AUTOPHAGY"]
    GAK -->|"associated with"| AUTOPHAGY
    DNAJC6["DNAJC6"]
    GAK -->|"associated with"| DNAJC6
    GENE_MUTATIONS["GENE MUTATIONS"]
    GAK -->|"associated with"| GENE_MUTATIONS
    PARK2["PARK2"]
    GAK -->|"associated with"| PARK2
    Autophagy(["Autophagy"])
    GAK -->|"associated with"| Autophagy
    Endocytosis(["Endocytosis"])
    GAK -->|"associated with"| Endocytosis
    neurodegeneration["neurodegeneration"]
    GAK -->|"implicated in"| neurodegeneration
    PARKINSON_S_DISEASE["PARKINSON'S DISEASE"]
    PARKINSON_S_DISEASE -->|"associated with"| GAK
    ALPHA_SYNUCLEIN["ALPHA-SYNUCLEIN"]
    ALPHA_SYNUCLEIN -->|"associated with"| GAK
    PARKIN["PARKIN"]
    PARKIN -->|"associated with"| GAK
    LRRK2["LRRK2"]
    LRRK2 -->|"associated with"| GAK
    INPP5F["INPP5F"]
    INPP5F -->|"associated with"| GAK
    style GAK fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0