concept

HIF2A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about HIF2A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

35Connections

0Hypotheses

0Analyses

21Outgoing

14Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	HIF2A
Key Genes/Proteins	BMAL1
Related Diseases	Myocardial Injury, Cancer, Ms, Cardiac, Pain
Related Pathways	Hypoxia Response

Wiki Pages (4)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    HIF2A["HIF2A"]
    HIF2A -->|"modulates"| Myocardial_Injury["Myocardial Injury"]
    HIF2A -->|"regulates"| Circadian_Rhythm["Circadian Rhythm"]
    HIF2A -->|"mediates"| Hypoxia_Response["Hypoxia Response"]
    HIF2A -->|"regulates"| Cancer["Cancer"]
    HIF2A -->|"interacts"| Ms["Ms"]
    HIF2A -->|"regulates"| Cardiac["Cardiac"]
    BMAL1["BMAL1"] -->|"binds"| HIF2A
    DNA["DNA"] -->|"interacts"| HIF2A
    BANG["BANG"] -->|"regulates"| HIF2A
    AREG["AREG"] -->|"regulates"| HIF2A
    CANCER["CANCER"] -->|"regulates"| HIF2A

Outgoing (21)

Target	Relation	Type	Str
Myocardial Injury	modulates	phenotype	0.95
Circadian Rhythm	regulates	process	0.90
Myocardial Injury	involved_in	disease	0.88
Myocardial Injury	regulates	disease	0.85
Heart	expressed_in	cell_type	0.85
cardiomyocyte	expressed_in	cell_type	0.85
Hypoxia Response	mediates	pathway	0.80
Cancer	regulates	disease	0.65
Ms	interacts_with	disease	0.65
Cardiac	regulates	disease	0.65
Pain	regulates	disease	0.65
CANCER	regulates	gene	0.60
Circadian Rhythm	interacts_with	pathway	0.60
AND	activates	gene	0.60
BANG	regulates	gene	0.60
BMAL1	regulates	gene	0.60
AREG	therapeutic_target	gene	0.60
Rb	regulates	protein	0.60
App	regulates	protein	0.60
oxidative stress response	participates_in	pathway	0.60
MYOCARDIAL_INJURY	regulates	phenotype	0.56

Incoming (14)

Source	Relation	Type	Str
BMAL1	associated_with	gene	0.90
BMAL1	forms_heterodimer_with	gene	0.90
BMAL1	binds	gene	0.80
BMAL1	interacts_with	protein	0.72
BMAL1	regulates	gene	0.60
DNA	interacts_with	gene	0.60
BANG	regulates	gene	0.60
AREG	regulates	gene	0.60
AREG	therapeutic_target	gene	0.60
CANCER	regulates	gene	0.60
BMAL1	activates	gene	0.60
AREG	targets	gene	0.60
BMAL1	targets	gene	0.60
AREG	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

HIF2A

Understanding Entity Pages

Wiki Pages (4)

BMAL1 Protein

VHL Gene