concept

HPA AXIS RELATED GENES

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about HPA AXIS RELATED GENES: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

23Connections

0Hypotheses

0Analyses

9Outgoing

14Incoming

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💡 Concept Info

Name	HPA AXIS RELATED GENES
Key Genes/Proteins	CRHBP, FKBP5, NR3C1, CRHR1, DNA, AND
Related Diseases	Depression
Related Pathways	Epigenetic

Pathway Diagram

graph TD
    HPA_AXIS_RELATED_GENES["HPA AXIS RELATED GENES"]
    HPA_AXIS_RELATED_GENES ---|"associated"| Depression["Depression"]
    HPA_AXIS_RELATED_GENES ---|"associated"| CRHBP["CRHBP"]
    HPA_AXIS_RELATED_GENES ---|"associated"| FKBP5["FKBP5"]
    HPA_AXIS_RELATED_GENES ---|"associated"| Epigenetic["Epigenetic"]
    HPA_AXIS_RELATED_GENES ---|"associated"| NR3C1["NR3C1"]
    Methylation["Methylation"] -->|"modulates"| HPA_AXIS_RELATED_GENES
    GENES["GENES"] ---|"associated"| HPA_AXIS_RELATED_GENES
    DNA["DNA"] ---|"associated"| HPA_AXIS_RELATED_GENES
    TNF["TNF"] ---|"associated"| HPA_AXIS_RELATED_GENES
    CRHR1["CRHR1"] ---|"associated"| HPA_AXIS_RELATED_GENES
    DEPRESSION["DEPRESSION"] ---|"associated"| HPA_AXIS_RELATED_GENES

Outgoing (9)

Target	Relation	Type	Str
Depression	associated_with	disease	0.65
CRHBP	associated_with	gene	0.60
FKBP5	associated_with	gene	0.60
Epigenetic	associated_with	pathway	0.60
NR3C1	associated_with	gene	0.60
CRHR1	associated_with	gene	0.60
DNA	associated_with	gene	0.60
AND	associated_with	gene	0.60
GENES	associated_with	gene	0.60

Incoming (14)

Source	Relation	Type	Str
Methylation	modulates	entity	0.90
GENES	associated_with	gene	0.60
DNA	associated_with	gene	0.60
TNF	associated_with	gene	0.60
CRHR1	associated_with	gene	0.60
DEPRESSION	associated_with	gene	0.60
TNF-ALPHA	associated_with	gene	0.60
CRH	associated_with	gene	0.60
IL-6	associated_with	gene	0.60
JUN	associated_with	gene	0.60
NR3C1	associated_with	gene	0.60
AND	associated_with	gene	0.60
CRHBP	associated_with	gene	0.60
FKBP5	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found