concept

MEF2 TARGET GENES

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MEF2 TARGET GENES: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

19Connections
0Hypotheses
0Analyses
9Outgoing
9Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameMEF2 TARGET GENES
Key Genes/ProteinsHDAC4, HDAC7, PI3K, HDAC, AND, GENES
Related DiseasesTumor, ALS
Related PathwaysPi3K/Akt

Wiki Pages (5)

Knowledge base pages for this entity

MEF2B (Myocyte Enhancer Factor 2B)

gene · 2829 words

HDAC9 Protein

protein · 1709 words

CREB-Independent Neuronal Survival Pathways in Neurodegeneration

mechanism · 1441 words

MEF2D Protein - Myocyte Enhancer Factor 2D

protein · 866 words

HDAC4 Gene

gene · 638 words

Pathway Diagram

graph TD
    MEF2_TARGET_GENES["MEF2 TARGET GENES"]
    MEF2_TARGET_GENES -->|"inhibits"| PI3K["PI3K"]
    MEF2_TARGET_GENES -->|"inhibits"| Pi3K_Akt["Pi3K/Akt"]
    MEF2_TARGET_GENES -->|"inhibits"| HDAC["HDAC"]
    MEF2_TARGET_GENES -->|"inhibits"| AND["AND"]
    MEF2_TARGET_GENES -->|"inhibits"| GENES["GENES"]
    HDAC4["HDAC4"] -->|"downregulates"| MEF2_TARGET_GENES
    PI3K -->|"regulates"| MEF2_TARGET_GENES
    GENES -->|"inhibits"| MEF2_TARGET_GENES
    AKT["AKT"] -->|"inhibits"| MEF2_TARGET_GENES
    HDAC -->|"inhibits"| MEF2_TARGET_GENES
    AND -->|"inhibits"| MEF2_TARGET_GENES

Outgoing (9)

TargetRelationTypeStr
Tumorassociated_withdisease0.65
ALSassociated_withdisease0.65
HDAC7associated_withgene0.60
PI3Kinhibitsgene0.60
Pi3K/Aktinhibitspathway0.60

Incoming (10)

SourceRelationTypeStr
HDAC4downregulatesprotein0.95
HDAC4associated_withgene0.60
GENESinhibitsgene0.60
AKTinhibitsgene0.60
HDACinhibitsgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found