Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PP1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | PP1 |
| Function | Pp1 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes. |
| Molecular Weight | 37 kDa |
| GeneCards | PP1 |
| Human Protein Atlas | PP1 |
| Associated Diseases | ALS |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["PP1"]
N1["PPP1R7"]
N1 -->|"component of"| N0
N2["ALS"]
N0 -->|"associated with"| N2
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
class N1 gene
class N2 disease| Target | Relation | Type | Str |
|---|---|---|---|
| ALS | associated_with | disease | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| PPP1R7 | component_of | gene | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Temporal SPP1 Inhibition During Critical Windows | 0.650 | neuroinflammation | What molecular mechanisms mediate SPP1-i |
Scientific analyses that reference this entity
neuroinflammation | 2026-04-15 | 1 hypotheses Top: 0.650
synaptic biology | 2026-04-07 | 0 hypotheses
neurodegeneration | 2026-04-06 | 0 hypotheses
neuroinflammation | 2026-04-06 | 0 hypotheses
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity