gene

RALB

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RALB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

16Connections
0Hypotheses
0Analyses
6Outgoing
10Incoming

Summary

RALB is a gene implicated in neurodegeneration research. Key relationships include: associated with, expressed in, implicated in. Associated with Als, Ms. Connected to 17 entities in the SciDEX knowledge graph.

View on Wiki →

🧬 Gene Info
Gene SymbolRALB
AliasesPage for RALB Gene, Page for RALB Protein
Chromosome2p22.3
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary ExpressionBrain (cerebral cortex, hippocampus, cerebellum), Lung, Liver, Kidney
Molecular Weight23 kDa
Amino Acids206 aa
UniProt IDP11234
NCBI Gene ID5878
Ensembl IDENSG00000128045
OMIM179897
GeneCardsRALB
Human Protein AtlasRALB
Symbol [@ralb2020] RALB [@ral2019] [@ralb2013] Full NameRAS-Related Protein Ral-B
Associated DiseasesAls, Ms
KG Connections16 knowledge graph edges
DatabasesGeneCardsHPASTRING
🔮 Predicted Structure: RALB — AlphaFold P11234 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (6)

Knowledge base pages for this entity

Canonical Page

RALB Gene - RAS-Related Protein Ral-B

gene · 1038 words

RRAS2 — Related RAS Virus (R-Ras) Family Member 2

gene · 2759 words

WDFY3 Gene

gene · 1245 words

RALB Protein - RAS-Related Protein Ral-B

protein · 1126 words

Proteins

index · 296 words

Genes

index · 271 words

Pathway Diagram

graph TD
    RALB["<b>RALB</b>"]
    Als{"Als"}
    RALB -->|"associated with"| Als
    Ms{"Ms"}
    RALB -->|"associated with"| Ms
    AUTOPHAGY_RELATED_GENES["AUTOPHAGY-RELATED GENES"]
    RALB -->|"associated with"| AUTOPHAGY_RELATED_GENES
    GNAI3["GNAI3"]
    RALB -->|"expressed in"| GNAI3
    WIPI1["WIPI1"]
    RALB -->|"expressed in"| WIPI1
    Autophagy(["Autophagy"])
    RALB -->|"associated with"| Autophagy
    neurodegeneration["neurodegeneration"]
    RALB -->|"implicated in"| neurodegeneration
    MIRNAS["MIRNAS"]
    MIRNAS -->|"associated with"| RALB
    C9ORF72["C9ORF72"]
    C9ORF72 -->|"expressed in"| RALB
    CD8["CD8"]
    CD8 -->|"associated with"| RALB
    LRRK2["LRRK2"]
    LRRK2 -->|"expressed in"| RALB
    IMMUNE_INFILTRATION["IMMUNE INFILTRATION"]
    IMMUNE_INFILTRATION -->|"associated with"| RALB
    MICRORNAS["MICRORNAS"]
    MICRORNAS -->|"associated with"| RALB
    AUTOPHAGY["AUTOPHAGY"]
    AUTOPHAGY -->|"associated with"| RALB
    GBA["GBA"]
    GBA -->|"expressed in"| RALB
    WDFY3["WDFY3"]
    WDFY3 -->|"expressed in"| RALB
    PIK3CB["PIK3CB"]
    PIK3CB -->|"expressed in"| RALB
    style RALB fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (6)

TargetRelationTypeStr
Alsassociated_withdisease0.65
Msassociated_withdisease0.65
GNAI3expressed_ingene0.60
WIPI1expressed_ingene0.60
AUTOPHAGY-RELATED GENESassociated_withgene0.60

Incoming (10)

SourceRelationTypeStr
C9ORF72expressed_ingene0.60
CD8associated_withgene0.60
LRRK2expressed_ingene0.60
GBAexpressed_ingene0.60
WDFY3expressed_ingene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found