Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RALB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
RALB is a gene implicated in neurodegeneration research. Key relationships include: associated with, expressed in, implicated in. Associated with Als, Ms. Connected to 17 entities in the SciDEX knowledge graph.
| Gene Symbol | RALB |
| Aliases | Page for RALB Gene, Page for RALB Protein |
| Chromosome | 2p22.3 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | Brain (cerebral cortex, hippocampus, cerebellum), Lung, Liver, Kidney |
| Molecular Weight | 23 kDa |
| Amino Acids | 206 aa |
| UniProt ID | P11234 |
| NCBI Gene ID | 5878 |
| Ensembl ID | ENSG00000128045 |
| OMIM | 179897 |
| GeneCards | RALB |
| Human Protein Atlas | RALB |
| Symbol [@ralb2020] RALB [@ral2019] [@ralb2013] Full Name | RAS-Related Protein Ral-B |
| Associated Diseases | Als, Ms |
| KG Connections | 16 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
RALB["<b>RALB</b>"]
Als{"Als"}
RALB -->|"associated with"| Als
Ms{"Ms"}
RALB -->|"associated with"| Ms
AUTOPHAGY_RELATED_GENES["AUTOPHAGY-RELATED GENES"]
RALB -->|"associated with"| AUTOPHAGY_RELATED_GENES
GNAI3["GNAI3"]
RALB -->|"expressed in"| GNAI3
WIPI1["WIPI1"]
RALB -->|"expressed in"| WIPI1
Autophagy(["Autophagy"])
RALB -->|"associated with"| Autophagy
neurodegeneration["neurodegeneration"]
RALB -->|"implicated in"| neurodegeneration
MIRNAS["MIRNAS"]
MIRNAS -->|"associated with"| RALB
C9ORF72["C9ORF72"]
C9ORF72 -->|"expressed in"| RALB
CD8["CD8"]
CD8 -->|"associated with"| RALB
LRRK2["LRRK2"]
LRRK2 -->|"expressed in"| RALB
IMMUNE_INFILTRATION["IMMUNE INFILTRATION"]
IMMUNE_INFILTRATION -->|"associated with"| RALB
MICRORNAS["MICRORNAS"]
MICRORNAS -->|"associated with"| RALB
AUTOPHAGY["AUTOPHAGY"]
AUTOPHAGY -->|"associated with"| RALB
GBA["GBA"]
GBA -->|"expressed in"| RALB
WDFY3["WDFY3"]
WDFY3 -->|"expressed in"| RALB
PIK3CB["PIK3CB"]
PIK3CB -->|"expressed in"| RALB
style RALB fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0| Source | Relation | Type | Str |
|---|---|---|---|
| C9ORF72 | expressed_in | gene | 0.60 |
| CD8 | associated_with | gene | 0.60 |
| LRRK2 | expressed_in | gene | 0.60 |
| GBA | expressed_in | gene | 0.60 |
| WDFY3 | expressed_in | gene | 0.60 |
| PIK3CB | expressed_in | gene | 0.60 |
| MIRNAS | associated_with | gene | 0.60 |
| IMMUNE INFILTRATION | associated_with | gene | 0.60 |
| MICRORNAS | associated_with | gene | 0.60 |
| AUTOPHAGY | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||