RPL23

Understanding Entity Pages

This page aggregates everything SciDEX knows about RPL23: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Comprehensive information about RPL23 (Ribosomal Protein L23), a component of the 60S ribosomal subunit involved in protein synthesis, p53 activation, and ribosomal stress responses in neurodegeneration.

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flowchart TD
    N0["RPL23"]
    N1["SNORA13"]
    N1 -->|"interacts with"| N0
    N2["free ribosomal proteins"]
    N0 -->|"modulates"| N2
    N3["Parkinson"]
    N0 -->|"causes"| N3
    N4["Als"]
    N0 -->|"activates"| N4
    N5["Senescence"]
    N0 -->|"activates"| N5
    N6["RNA"]
    N0 -->|"activates"| N6
    N7["P53"]
    N0 -->|"activates"| N7
    N8["Rb"]
    N0 -->|"activates"| N8
    N9["PARKINSON'S DISEASE"]
    N9 -->|"activates"| N0
    N10["TP53"]
    N10 -->|"causes"| N0
    N11["PARKINSON"]
    N11 -->|"causes"| N0
    N7 -->|"activates"| N0
    N12["FBXO7"]
    N12 -->|"activates"| N0
    N13["MDM2"]
    N13 -->|"activates"| N0

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N2 protein
    class N3 disease
    class N4 disease
    class N5 disease
    class N6 gene
    class N7 gene
    class N8 protein
    class N9 gene
    class N10 gene
    class N11 gene
    class N12 gene
    class N13 gene