gene

SLC17A9

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SLC17A9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

30Connections

0Hypotheses

0Analyses

21Outgoing

9Incoming

No summary available yet. View on Wiki →

🧬 Gene Info

Gene Symbol	SLC17A9
Full Name	Solute Carrier Family 17 Member 9
Aliases	VNUT, CT64, ENT3, SLC17A9
Chromosome	17q21.32
Protein Type	Transporter
Function	is a critical transmembrane protein responsible for the storage and release of nucleotides, particularly adenosine triphosphate (ATP), from secretory vesicles.
Molecular Weight	52 kDa
Amino Acids	477 aa
Exons	14
Gene Type	Protein coding
Pathways	Inflammasome
UniProt ID	Q9NRH3 (SLC9A_HUMAN)
NCBI Gene ID	131670
Ensembl ID	ENSG00000139233
GeneCards	SLC17A9
Human Protein Atlas	SLC17A9
Associated Diseases	neurodegeneration
Interactions	P2X7, IL-1, Interleukin, Cytokine, Ras, INFLAMMATION
KG Connections	30 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SLC17A9 — AlphaFold Q9NRH3 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

slc17a9

gene · 2463 words

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Genes

index · 271 words

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Pathway Diagram

graph TD
    SLC17A9["<b>SLC17A9</b>"]
    Als{"Als"}
    SLC17A9 -->|"activates"| Als
    ALS{"ALS"}
    SLC17A9 -->|"activates"| ALS
    Inflammation{"Inflammation"}
    SLC17A9 -->|"activates"| Inflammation
    Heart_Failure{"Heart Failure"}
    SLC17A9 -->|"activates"| Heart_Failure
    IL_1(["IL-1"])
    SLC17A9 -->|"activates"| IL_1
    NLRP3(["NLRP3"])
    SLC17A9 -->|"associated_with"| NLRP3
    P2RX7(["P2RX7"])
    P2RX7 -->|"associated_with"| SLC17A9
    ATP(["ATP"])
    ATP -->|"associated_with"| SLC17A9
    INFLAMMATION(["INFLAMMATION"])
    INFLAMMATION -->|"activates"| SLC17A9
    P2X7(["P2X7"])
    P2X7 -->|"activates"| SLC17A9
    style SLC17A9 fill:#1a3a4a,stroke:#ce93d8,stroke-width:3px,color:#ce93d8

Outgoing (21)

Target	Relation	Type	Str
Als	activates	disease	0.65
ALS	activates	disease	0.65
Inflammation	activates	disease	0.65
Heart Failure	activates	disease	0.65
NLRP3	associated_with	gene	0.60
P2X7	activates	gene	0.60
P2RX7	associated_with	gene	0.60
P2RX7	transports	gene	0.60
IL-1	activates	gene	0.60
Inflammasome	activates	pathway	0.60
Neuron	associated_with	cell_type	0.60
AND	associated_with	gene	0.60
NEURON	associated_with	gene	0.60
ATP	associated_with	gene	0.60
Interleukin	activates	protein	0.60
Cytokine	activates	protein	0.60
ATP	transports	gene	0.60
Neuron	transports	cell_type	0.60
Ras	activates	protein	0.60
neurons	expressed_in	cell_type	0.60
Neuron	expressed_in	cell_type	0.55

Incoming (9)

Source	Relation	Type	Str
P2RX7	associated_with	gene	0.60
P2X7	activates	gene	0.60
NLRP3	associated_with	gene	0.60
NLRP3	transports	gene	0.60
ATP	associated_with	gene	0.60
INFLAMMATION	activates	gene	0.60
IL-1	activates	gene	0.60
NLRP3	co_mentioned	gene	0.40
P2RX7	co_mentioned	gene	0.40

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found