protein

SYN1PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SYN1PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Synapsin I (also known as Synapsin-1 or SYN1) is a neuronal phosphoprotein that plays a crucial role in regulating synaptic transmission and synaptic vesicle dynamics at the presynaptic terminal.

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🔬 Protein Info

Gene Symbol	SYN1PROTEIN
Full Name	Synapsin I
Protein Type	Protein
Function	is a neuronal phosphoprotein that plays a crucial role in regulating synaptic transmission and synaptic vesicle dynamics at the presynaptic terminal.
Molecular Weight	80 kDa
UniProt ID	Search UniProt
GeneCards	SYN1PROTEIN
Human Protein Atlas	SYN1PROTEIN
C-terminal Domain	Rich in proline residues, facilitating interactions with actin filaments and other cytoskeletal elements through its ability to bind F-actin
Linker Region	Provides structural flexibility and mediates protein-protein interactions essential for vesicle clustering
Phosphorylation Sites	Contains multiple consensus sequences for phosphorylation by various kinases, enabling rapid modulation of function in response to neuronal activity
Associated Diseases	aging, Als, Alzheimer, Alzheimer'S Disease
Known Drugs/Compounds	rapamycin, RAPAMYCIN
Interactions	ACTB, Actin, ADAM10, AKT, ALZHEIMER, ALZHEIMER DISEASE
KG Connections	470 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: SYN1PROTEIN — AlphaFold SEARCH Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Synapsin I Protein

protein · 1125 words

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Pathway Diagram

graph TD
    SYN1PROTEIN["SYN1PROTEIN"]
    neurodegeneration["neurodegeneration"]
    SYN1PROTEIN -->|"implicated_in"| neurodegeneration
    style SYN1PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity