Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about als9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet. View on Wiki →
| Gene Symbol | ANG |
| Full Name | Amyotrophic Lateral Sclerosis 9 |
| Aliases | Page for ALS9 |
| Chromosome | 14q11.2 |
| Protein Type | Secreted ribonuclease |
| Function | is a genetic subtype of familial amyotrophic lateral sclerosis caused by mutations in the ANG gene (Angiogenin). |
| Primary Expression | Broad, high in liver, brain, and motor neurons |
| Molecular Weight | 14.9 kDa |
| Amino Acids | 147 aa |
| Pathways | PI3K |
| UniProt ID | P03950 |
| Ensembl ID | ENSG00000100939 |
| OMIM | 105400 |
| GeneCards | ANG |
| Human Protein Atlas | ANG |
| Associated Diseases | ALS is neuroprotection rather than angiogenesis |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
ALS9["ALS9"]
ALS9 -->|"implicated in"| neurodegeneration["neurodegeneration"]
ALS9 ---|"associated"| Als["Als"]
ALS9 ---|"associated"| Glaucoma["Glaucoma"]
ALS9 ---|"associated"| Amyotrophic_Lateral_Sclerosis["Amyotrophic Lateral Sclerosis"]
ALS9 ---|"associated"| TARDBP["TARDBP"]
ALS9 ---|"associated"| ALS7["ALS7"]
ALS2["ALS2"] ---|"associated"| ALS9
FIG4["FIG4"] ---|"associated"| ALS9
FUS["FUS"] ---|"associated"| ALS9
ALS8["ALS8"] ---|"associated"| ALS9
ALSIN["ALSIN"] ---|"associated"| ALS9| Target | Relation | Type | Str |
|---|---|---|---|
| Als | associated_with | disease | 0.65 |
| Glaucoma | associated_with | disease | 0.65 |
| Amyotrophic Lateral Sclerosis | associated_with | disease | 0.65 |
| TARDBP | associated_with | gene | 0.60 |
| ALS7 | associated_with | gene | 0.60 |
| ALS10 | associated_with | gene | 0.60 |
| SOD1 | associated_with | gene | 0.60 |
| ALS | associated_with | gene | 0.60 |
| GENES | associated_with | gene | 0.60 |
| MOTOR NEURONS | associated_with | gene | 0.60 |
| DNA | associated_with | gene | 0.60 |
| AMYOTROPHIC LATERAL SCLEROSIS | associated_with | gene | 0.60 |
| GENE MUTATIONS | associated_with | gene | 0.60 |
| benchmark_ot_ad_answer_key:ALS9 | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||