biomarker 1,465 words KG: NPTXR
Contents

Neuronal Pentraxin Receptor (NPTXR)

🔬 Protein Info
Gene SymbolNPTXR
Full NameNeuronal Pentraxin Receptor
Chromosome22q13.1.
Protein TypeReceptor
FunctionNeuronal Pentraxin Receptor (NPTXR) is a membrane protein that serves as the primary receptor for the neuronal pentraxin family, including NPTX1 and NPTX2.
Molecular Weight50 kDa
Ensembl IDENSG00000162591
GeneCardsNPTXR
Human Protein AtlasNPTXR
ELISAStandard method for CSF and plasma
SimOAFor ultra-sensitive detection
Western blotFor protein analysis
IHCFor tissue localization
Associated DiseasesAls, Alzheimer, Dementia, Diabetes, Ms
InteractionsBDNF, DEMENTIA, ROS, TRKB
KG Connections19 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Related Hypotheses (15)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.88
SASP-Mediated Cholinergic Synapse Disruption
Score: 0.76
Sleep Spindle-Synaptic Plasticity Enhancement
Score: 0.72
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Retinal Vascular Microcirculation Rescue
Score: 0.72
Endothelial Glycocalyx Regeneration via Syndecan-1 Upregulat
Score: 0.71
Excitatory Neuron Vulnerability via SLC17A7 Downregulation
Score: 0.67
Synaptic Phosphatidylserine Masking via Annexin A1 Mimetics
Score: 0.62
Pharmacological Enhancement of APOE4 Glycosylation
Score: 0.62
Trans-Synaptic Adhesion Molecule Modulation
Score: 0.54
Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.51
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
Context-Dependent CRISPR Activation in Specific Neuronal Sub
Score: 0.68
Partial Neuronal Reprogramming via Modified Yamanaka Cocktai
Score: 0.67
Programmable Neuronal Circuit Repair via Epigenetic CRISPR
Score: 0.63

Related Analyses (7)

Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · completed
Metabolic reprogramming in neurodegenerative disease
neurodegeneration · completed

Knowledge Graph (12 edges)

NPTXR activates BDNF
NPTXR activates TRKB
IL6 associated_with NPTXR
NPTXR associated_with STAT3
ROS activates NPTXR
NPTXR activates DEMENTIA
NPTXR activates Aging
NPTXR activates Dementia
JAK associated_with NPTXR
NPTXR associated_with DEMENTIA

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