biomarker 1,465 words KG: NPTXR 2026-03-24
kind:biomarkersection:biomarkersstate:published
Contents

Neuronal Pentraxin Receptor (NPTXR)

🔬 Protein Info
Gene SymbolNPTXR
Full NameNeuronal Pentraxin Receptor
Chromosome22q13.1.
Protein TypeReceptor
FunctionNeuronal Pentraxin Receptor (NPTXR) is a membrane protein that serves as the primary receptor for the neuronal pentraxin family, including NPTX1 and NPTX2.
Molecular Weight50 kDa
Ensembl IDENSG00000162591
GeneCardsNPTXR
Human Protein AtlasNPTXR
ELISAStandard method for CSF and plasma
SimOAFor ultra-sensitive detection
Western blotFor protein analysis
IHCFor tissue localization
Associated DiseasesAls, Alzheimer, Dementia, Diabetes, Ms
InteractionsBDNF, TRKB, DEMENTIA, ROS
KG Connections20 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (15)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.62
SASP-Mediated Cholinergic Synapse Disruption
Score: 0.56
Retinal Vascular Microcirculation Rescue
Score: 0.54
Endothelial Glycocalyx Regeneration via Syndecan-1 Upregulat
Score: 0.50
Sleep Spindle-Synaptic Plasticity Enhancement
Score: 0.49

Related Analyses (7)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Metabolic reprogramming in neurodegenerative disease
neurodegeneration · completed
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · completed

Knowledge Graph (12 edges)

NPTXR activates BDNF
NPTXR activates TRKB
NPTXR associated_with STAT3
NPTXR activates DEMENTIA
NPTXR activates Aging
NPTXR activates Dementia
NPTXR associated_with DEMENTIA
NPTXR associated_with ALZHEIMER
NPTXR associated_with AND
NPTXR associated_with ALZHEIMER'S DISEASE