gene 1,547 words KG: ADRA1B
Contents

ADRA1B — Alpha-1B Adrenergic Receptor

🧬 Gene Info
Gene SymbolADRA1B
Full NameAlpha-1B Adrenergic Receptor
Aliasesα1B-AR
Chromosome5q23.3
Protein FamilyAdrenergic receptors (GPCR)
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary ExpressionSmooth muscle, brain, heart
Amino Acids515 aa
UniProt IDP35368
NCBI Gene ID147
Ensembl IDENSG00000170175
GeneCardsADRA1B
Human Protein AtlasADRA1B
Gq protein activationActivates phospholipase Cβ (PLCβ)
PIP2 hydrolysisGenerates IP3 and DAG
Associated Diseasesneurodegeneration
InteractionsADRA1A, DRD1, DRD2, GRIA1, GRIN1, HCRTR1
KG Connections22 knowledge graph edges
DatabasesGeneCardsHPASTRING

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