gene 1,547 words KG: ADRA1B 2026-03-27
kind:genesection:genesstate:published
Contents

ADRA1B — Alpha-1B Adrenergic Receptor

🧬 Gene Info
Gene SymbolADRA1B
Full NameAlpha-1B Adrenergic Receptor
Aliasesα1B-AR
Chromosome5q23.3
Protein FamilyAdrenergic receptors (GPCR)
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary ExpressionSmooth muscle, brain, heart
Amino Acids515 aa
UniProt IDP35368
NCBI Gene ID147
Ensembl IDENSG00000170175
GeneCardsADRA1B
Human Protein AtlasADRA1B
Protein ClassG protein-coupled receptor
Associated Diseasesneurodegeneration
InteractionsDRD1, GRIA1, ADRA1A, HRH1, GRIN1, HCRTR1
KG Connections23 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (4)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.62
Orexin-Microglia Modulation Therapy
Score: 0.49
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.47
Piezoelectric Nanochannel BBB Disruption
Score: 0.41

Related Analyses (5)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
GBA-Synuclein Loop Therapeutics for PD
neurodegeneration · completed
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · completed

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (12)

Packard Center for ALS Research
institution · KG edge: activates
HRH3 Gene
gene · KG edge: activates
HRH1 Gene
gene · KG edge: activates
HCRTR1
gene · KG edge: activates
GRIN1 — NMDA Receptor Subunit 1
gene · KG edge: activates

Knowledge Graph (12 edges)

ADRA1B activates DRD1
ADRA1B activates GRIA1
ADRA1B activates ADRA1A
ADRA1B activates HRH1
ADRA1B activates GRIN1
ADRA1B activates HCRTR1
ADRA1B activates Rb
ADRA1B activates Ms
ADRA1B activates Als
ADRA1B activates Epigenetic