GRIN1

Understanding Entity Pages

This page aggregates everything SciDEX knows about GRIN1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

GRIN1 is a gene implicated in neurodegeneration research. Key relationships include: therapeutic target, activates, implicated in. Associated with Als, Inflammation, Ms. Connected to 30 entities in the SciDEX knowledge graph.

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graph TD
    GRIN1["<b>GRIN1</b>"]
    Ms{"Ms"}
    GRIN1 -->|"activates"| Ms
    Als{"Als"}
    GRIN1 -->|"activates"| Als
    Inflammation{"Inflammation"}
    GRIN1 -->|"therapeutic target"| Inflammation
    GRIN1 -->|"therapeutic target"| Als
    HCRTR1["HCRTR1"]
    GRIN1 -->|"activates"| HCRTR1
    Epigenetic(["Epigenetic"])
    GRIN1 -->|"activates"| Epigenetic
    Dna_Methylation(["Dna Methylation"])
    GRIN1 -->|"activates"| Dna_Methylation
    ADAM10["ADAM10"]
    GRIN1 -->|"therapeutic target"| ADAM10
    Oxidative_Stress(["Oxidative Stress"])
    GRIN1 -->|"therapeutic target"| Oxidative_Stress
    Nf__b(["Nf-Kappab"])
    GRIN1 -->|"therapeutic target"| Nf__b
    Apoptosis(["Apoptosis"])
    GRIN1 -->|"therapeutic target"| Apoptosis
    neurodegeneration["neurodegeneration"]
    GRIN1 -->|"implicated in"| neurodegeneration
    DRD2["DRD2"]
    DRD2 -->|"activates"| GRIN1
    HRH3["HRH3"]
    HRH3 -->|"activates"| GRIN1
    HCRTR2["HCRTR2"]
    HCRTR2 -->|"activates"| GRIN1
    ADRA1B["ADRA1B"]
    ADRA1B -->|"activates"| GRIN1
    DRD1["DRD1"]
    DRD1 -->|"activates"| GRIN1
    GRIA1["GRIA1"]
    GRIA1 -->|"activates"| GRIN1
    ADRA1A["ADRA1A"]
    ADRA1A -->|"activates"| GRIN1
    HRH1["HRH1"]
    HRH1 -->|"activates"| GRIN1
    GENES["GENES"]
    GENES -->|"therapeutic target"| GRIN1
    CAPN1["CAPN1"]
    CAPN1 -->|"therapeutic target"| GRIN1
    TTR["TTR"]
    TTR -->|"therapeutic target"| GRIN1
    LGALS3["LGALS3"]
    LGALS3 -->|"therapeutic target"| GRIN1
    style GRIN1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0