gene 1,227 words KG: DRD1
Contents

DRD1 Gene

🧬 Gene Info
Gene SymbolDRD1
Full NameDopamine Receptor D1
Chromosome5q35.2
Protein TypeReceptor
FunctionThe D1 receptor is a postsynaptic dopamine receptor that:
Primary ExpressionStriatum, Cortex, Nucleus accumbens, Olfactory bulb
PathwaysMAPK
UniProt IDP21709
NCBI Gene ID1817
Ensembl IDENSG00000184845
GeneCardsDRD1
Human Protein AtlasDRD1
Associated DiseasesAls, Alzheimer, Autism, Bipolar, Cancer
InteractionsADRA1A, ADRA1B, BDNF, CACNA1B, CACNA1H, CNR1
KG Connections298 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (16)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
CYP46A1 Overexpression Gene Therapy
Score: 0.77
Smartphone-Detected Motor Variability Correction
Score: 0.74
Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.72
Orexin-Microglia Modulation Therapy
Score: 0.71
Purinergic P2Y12 Inverse Agonist Therapy
Score: 0.70
Microglial Purinergic Reprogramming
Score: 0.70
Complement C1q Mimetic Decoy Therapy
Score: 0.69
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Complement C1QA Spatial Gradient in Cortical Layers
Score: 0.68
Excitatory Neuron Vulnerability via SLC17A7 Downregulation
Score: 0.67
Complement C1q Subtype Switching
Score: 0.66
Optogenetic Microglial Deactivation via Engineered Inhibitor
Score: 0.66
Complement-Mediated Synaptic Pruning Dysregulation
Score: 0.61
Correcting Gut Microbial Dopamine Imbalance to Support Syste
Score: 0.61
Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.56

Related Analyses (9)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived

See Also (15)

Astrocytes
cell · KG edge: regulates
Astrocytes
entity · KG edge: regulates
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
ADRA1A Gene
gene · KG edge: activates
ADRA1B — Alpha-1B Adrenergic Receptor
gene · KG edge: activates

Knowledge Graph (12 edges)

DRD1 participates_in dopaminergic_circuits
HTR2A associated_with DRD1
DISC1 associated_with DRD1
FKBP5 associated_with DRD1
NRG1 associated_with DRD1
DAO associated_with DRD1
BMAL1 associated_with DRD1
GRM4 associated_with DRD1
SYNGR1 associated_with DRD1
BDNF associated_with DRD1

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.