| Gene Symbol | CXCL12 |
| Protein Type | Gene |
| Function | CXCL12 is a highly conserved chemokine expressed throughout the central nervous system. |
| Primary Expression | the brain: - Neurons: High expression in cortex, hippocampus, cerebell |
| Pathways | Apoptosis, Autophagy, Cell Cycle, Chaperone, Epigenetic |
| UniProt ID | P48061 |
| GeneCards | CXCL12 |
| Human Protein Atlas | CXCL12 |
| Neurodevelopment | Guiding neuronal migration and axon pathfinding |
| Neurogenesis | Promoting neural stem cell proliferation and differentiation |
| Synaptic transmission | Modulating GABAergic and glutamatergic signaling |
| Neuroprotection | Activating anti-apoptotic pathways |
| Immune regulation | Controlling leukocyte trafficking |
| Associated Diseases | Als, Alzheimer, Cancer, Carcinoma, Depression |
| Interactions | adcy2, ADCY2, AGING, ALZHEIMER, ALZHEIMER'S DISEASE, AND |
| SciDEX Hypotheses | CCL2 Gradient Disruption via Astrocytic CXCL12 Upr |
| KG Connections | 183 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!