Contents

DLG4 Gene - PSD-95

🧬 Gene Info

Gene Symbol	DLG4
Full Name	Discs Large Homolog 4 / PSD-95
Aliases	DLG4/PSD-95 gene
Chromosome	8p21.2
Function	DLG4/PSD-95 performs critical synaptic functions[3]
Molecular Weight	95 kDa
Amino Acids	724 aa
Pathways	Dendritic Spine
UniProt ID	[P78352](https://www.uniprot.org/uniprot/P78352)
Ensembl ID	ENSG00000132587
GeneCards	DLG4
Human Protein Atlas	DLG4
Synaptic scaffolding	Organizes the postsynaptic density by anchoring NMDA receptors, AMPA receptors, and other signaling proteins
Synaptic transmission	Regulates glutamate receptor trafficking and function at excitatory synapses
Synaptic plasticity	Essential for long-term potentiation (LTP) and long-term depression (LTD) induction
Associated Diseases	Aging, Autism, Tinnitus, Williams' syndrome, autism spectrum disorders
Interactions	CASP3, NR3C1, FKBP5, FOS, PARP1, SYN1
KG Connections	167 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Knowledge Graph