| Gene Symbol | DLG4 |
| Full Name | Discs Large Homolog 4 / PSD-95 |
| Aliases | DLG4/PSD-95 gene |
| Chromosome | 8p21.2 |
| Function | DLG4/PSD-95 performs critical synaptic functions[3] |
| Molecular Weight | 95 kDa |
| Amino Acids | 724 aa |
| Pathways | Dendritic Spine |
| UniProt ID | [P78352](https://www.uniprot.org/uniprot/P78352) |
| Ensembl ID | ENSG00000132587 |
| GeneCards | DLG4 |
| Human Protein Atlas | DLG4 |
| Synaptic scaffolding | Organizes the postsynaptic density by anchoring NMDA receptors, AMPA receptors, and other signaling proteins |
| Synaptic transmission | Regulates glutamate receptor trafficking and function at excitatory synapses |
| Synaptic plasticity | Essential for long-term potentiation (LTP) and long-term depression (LTD) induction |
| Associated Diseases | Aging, Autism, autism spectrum disorders, Synaptic Integrity, Tinnitus, Williams' syndrome |
| Interactions | ACHE, ANXIETY, ARC, ATM, BDNF, BRCA1 |
| KG Connections | 166 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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