gene 1,240 words KG: ent-gene-8cc2e8f7
Contents

ABCD3 Gene

🧬 Gene Info
Gene SymbolABCD3
Chromosome1p22.1
Protein FamilyABC transporter subfamily D
Protein TypeTransporter
FunctionABCD3 functions as a peroxisomal membrane transporter
Primary Expressionmultiple tissues, with highest levels in liver, kidney, and brain
Subcellular LocalizationPeroxisomal membrane
Molecular Weight79.7 kDa
PathwaysTgf-Beta, Wnt
UniProt ID[O75323](https://www.uniprot.org/uniprot/O75323)
GeneCardsABCD3
Human Protein AtlasABCD3
Associated DiseasesAD, ALI, Als, Alzheimer, Cancer
InteractionsABCD1, ABCD2, Actin, ALS, ALZHEIMER, ALZHEIMER DISEASE
KG Connections473 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (9)

Liquid-Liquid Phase Separation Modifier Therapy
Score: 0.55
CYP46A1 Overexpression Gene Therapy
Score: 0.77
Phase-Separated Organelle Targeting
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72
Mitochondrial Transfer Pathway Enhancement
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
RNA Granule Nucleation Site Modulation
Score: 0.66
Miro1-Mediated Mitochondrial Trafficking Enhancement Therapy
Score: 0.55
Prohibitin-2 Mitochondrial Cross-Seeding Hub Disruption
Score: 0.47

Related Analyses (4)

Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (9)

ABCA2 Gene - ATP Binding Cassette Subfamily A Member 2
gene · KG edge: expressed_in
ABCD1 — ATP Binding Cassette Subfamily D Member 1
gene · KG edge: activates
ABCD2 — ATP Binding Cassette Subfamily D Member 2
gene · KG edge: activates
ABCG1 Gene
gene · KG edge: expressed_in
ABCG2 (BCRP) - ATP Binding Cassette Subfamily G Member
gene · KG edge: expressed_in

Knowledge Graph (2 edges)

ent-gene-8cc2e8f7 data_in benchmark_ot_ad_answer_key:ABCD3
benchmark_ot_ad_answer_key:ABCD3 data_in ent-gene-8cc2e8f7

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