| Gene Symbol | ALDH1A1 |
| Function | ALDH1A1 encodes aldehyde dehydrogenase 1A1, a cytosolic enzyme that catalyzes the oxidation of aldehydes to carboxylic acids. |
| Primary Expression | multiple brain regions:
- Substantia nigra pars compacta - dopaminergic neurons (high expression)
- Ventral tegmental area - dopaminergic neur |
| Pathways | Complement, Epigenetic, Ferroptosis, Metastasis, Notch |
| Ensembl ID | ENSG00000153208 |
| GeneCards | ALDH1A1 |
| Human Protein Atlas | ALDH1A1 |
| Substantia nigra pars compacta | dopaminergic neurons (high expression) |
| Ventral tegmental area | dopaminergic neurons |
| Striatum | medium spiny neurons |
| Retina | retinal pigment epithelium |
| Liver | hepatocytes |
| Associated Diseases | Aging, Als, Diabetes, Ms |
| Interactions | EGFR, SLC18A2, SLC6A3, CANCER, FERROPTOSIS, PARKINSON |
| KG Connections | 169 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |