gene 1,786 words KG: APOC1 2026-03-28
kind:genesection:genesstate:published
Contents

APOC1 Gene — Apolipoprotein C-I

🧬 Gene Info
Gene SymbolAPOC1
Full NameApolipoprotein C-I
Chromosome19
Molecular Weight~9 kDa
Amino Acids79 aa
Exons4
PathwaysInteraction
UniProt IDP02654
NCBI Gene ID341
Ensembl IDENSG00000130208
OMIM107710
GeneCardsAPOC1
Human Protein AtlasAPOC1
Protein Length79 amino acids
FeatureDetails
Associated Diseasesneurodegeneration
InteractionsAPOC2, SOAT1, ABCA2, LDLR, APOC3, APOE
KG Connections114 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (22)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Circadian-Synchronized LRP1 Pathway Activation
Score: 0.53
LRP1-Dependent Tau Uptake Disruption
Score: 0.44
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
CYP46A1 Overexpression Gene Therapy
Score: 0.63

Related Analyses (5)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Packard Center for ALS Research
institution · KG edge: degrades
Alzheimer Indonesia
institution · KG edge: degrades
CYP46A1 — Cholesterol 24-Hydroxylase
gene · KG edge: activates
APOC3 Gene
gene · KG edge: activates
APOC2 Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

APOC1 expressed_in MYELOID_CELLS
APOC1 activates APOC2
APOC1 activates SOAT1
APOC1 activates ABCA2
APOC1 regulates PSEN2
APOC1 regulates TAU
APOC1 activates LDLR
APOC1 activates APOC3
APOC1 transports LRP1
APOC1 transports SREBF1