| Gene Symbol | ATF4 |
| Full Name | Activating Transcription Factor 4 |
| Chromosome | 22q13.1 |
| Protein Type | Transcription Factor |
| Function | Amino acid metabolism: Upregulates genes involved in amino acid transport and synthesis |
| Molecular Weight | 38.6 kDa |
| Pathways | Apoptosis, Autophagy, Epigenetic, Er Stress, Ferroptosis |
| UniProt ID | [P18848](https://www.uniprot.org/uniprot/P18848) |
| GeneCards | ATF4 |
| Human Protein Atlas | ATF4 |
| Associated Diseases | Aging, Atherosclerosis, cancer, Glioblastoma, Tumor |
| Known Drugs/Compounds | rapamycin |
| Interactions | ACSL4, Actin, AGING, AKT, AMPK, AMYLOID |
| SciDEX Hypotheses | ATF4-DDIT3 stress signaling indirectly represses M |
| KG Connections | 565 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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