gene 1,415 words KG: CCL25 2026-03-31
kind:genesection:genesstate:published
Contents

CCL25 Gene

🧬 Gene Info
Gene SymbolCCL25
Chromosome19p13.2
Protein TypeChemokine
FunctionCCL25 has distinct functions in immune development and homeostasis:
Primary ExpressionHigh on small intestinal T cells, thymocytes, and some inflammatory cells
Molecular Weight~9.4 kDa
PathwaysPI3K, MAPK
NCBI Gene ID6374
GeneCardsCCL25
Human Protein AtlasCCL25
Protein ClassChemokine
Cell TypeExpression Level
Thymic epithelial cellsHigh
Small intestineHigh
Dendritic cellsModerate
Associated DiseasesDepression, Inflammation, Neuroinflammation
InteractionsCX3CR1, CXCR5, CX3CL1
KG Connections29 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.50
Gut Barrier Permeability-α-Synuclein Axis Modulation
Score: 0.49
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Optogenetic Microglial Deactivation via Engineered Inhibitor
Score: 0.38

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: biomarker_for
Alzheimer Indonesia
institution · KG edge: biomarker_for
CX3CR1 Modulation Therapy for Neurodegeneration
idea · KG edge: activates
Autoimmune Hypothesis in Alzheimer's Disease
hypothesis · KG edge: therapeutic_target
CXCR5 Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

CCL25 biomarker_for CXCL10
CCL25 activates CX3CR1
CCL25 associated_with CNP
CCL25 associated_with MMP1
CCL25 associated_with NEFL
CCL25 associated_with RBFOX3
CCL25 biomarker_for INFLAMMATION
CCL25 biomarker_for Ms
CCL25 biomarker_for Inflammation
CCL25 associated_with Depression