| Gene Symbol | CPT2 |
| Aliases | Carnitine Palmitoyltransferase 2 |
| Chromosome | 1p32.3 |
| Protein Type | Enzyme |
| Function | encodes a mitochondrial enzyme that catalyzes the conversion of acylcarnitine esters back to free carnitine and fatty acyl-CoA esters. |
| Amino Acids | 659 aa |
| Pathways | Amyloid, Lipid Metabolism, Mitochondrial Function, Oxidative Phosphorylation |
| Ensembl ID | ENSG00000157184 |
| GeneCards | CPT2 |
| Human Protein Atlas | CPT2 |
| Transmembrane anchor | A single transmembrane helix that localizes the protein to the inner mitochondrial membrane |
| Catalytic domain | The bulk of the protein faces the mitochondrial matrix where catalysis occurs |
| Substrate binding pocket | Contains residues for carnitine and acyl-CoA binding |
| Associated Diseases | Als, Cancer, Cardiac, Heart Failure, Tumor |
| Interactions | ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, AMYLOID-Β PLAQUES, CANCER, IDH2 |
| KG Connections | 71 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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