| Gene Symbol | CPT2 |
| Aliases | Carnitine Palmitoyltransferase 2 |
| Chromosome | 1p32.3 |
| Protein Type | Enzyme |
| Function | encodes a mitochondrial enzyme that catalyzes the conversion of acylcarnitine esters back to free carnitine and fatty acyl-CoA esters. |
| Amino Acids | 659 aa |
| Pathways | Amyloid, Lipid Metabolism, Mitochondrial Function, Oxidative Phosphorylation |
| Ensembl ID | ENSG00000157184 |
| GeneCards | CPT2 |
| Human Protein Atlas | CPT2 |
| Transmembrane anchor | A single transmembrane helix that localizes the protein to the inner mitochondrial membrane |
| Catalytic domain | The bulk of the protein faces the mitochondrial matrix where catalysis occurs |
| Substrate binding pocket | Contains residues for carnitine and acyl-CoA binding |
| Associated Diseases | Als, Cancer, Cardiac, Heart Failure, Tumor |
| Interactions | SLC44A2, MUL1, PVALB, SST, IDH2, TAU |
| KG Connections | 73 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |