gene 960 words KG: ELAVL4 2026-03-24
kind:genesection:genesstate:published
Contents

ELAVL4 Gene

🧬 Gene Info
Gene SymbolELAVL4
Full NameELAV Like Neuron-Specific RNA Binding Protein 4
Chromosome1p31.3
FunctionELAVL4 encodes ELAV-like protein 4 (also known as HU antigen D), a neuron-specific RNA-binding protein.
Primary Expressionneurons of the central and peripheral nervous systems
Molecular Weight38 kDa
Amino Acids326 aa
PathwaysApoptosis, Autophagy, Glutamate Signaling, Stem Cell, glutamate signaling
UniProt ID[P26378](https://www.uniprot.org/uniprot/P26378)
Ensembl IDENSG00000162374
GeneCardsELAVL4
Human Protein AtlasELAVL4
Associated DiseasesALS, dementia, frontotemporal, neurodegeneration
InteractionsMAPT, TAU, AUTOPHAGY, PIKFYVE, DEMENTIA, RNA
KG Connections46 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (10)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Phase-Separated Organelle Targeting
Score: 0.52
Stress Granule Phase Separation Modulators
Score: 0.49
RNA Granule Nucleation Site Modulation
Score: 0.48
Cryptic Exon Silencing Restoration
Score: 0.46

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (7)

Packard Center for ALS Research
institution · KG edge: activates
Dementia Australia
institution · KG edge: activates
MAPT (Microtubule-Associated Protein Tau) Gene
gene · KG edge: activates
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: activates
glutamate
general · KG edge: activates

Knowledge Graph (12 edges)

ELAVL4 activates MAPT
ELAVL4 regulates MAPT
ELAVL4 activates TAU
ELAVL4 associated_with MAPT
ELAVL4 participates_in glutamate signaling
ELAVL4 co_mentioned MAPT
ELAVL4 co_expressed_with MAPT
ELAVL4 associated_with frontotemporal
ELAVL4 associated_with neurodegeneration
ELAVL4 activates Dementia