gene 740 words KG: FOSB 2026-03-22
kind:genesection:genesstate:published
Contents

FOSB Gene

🧬 Gene Info
Gene SymbolFOSB
Full NameFBJ Murine Osteosarcoma Viral Oncogene Homolog B
Chromosome19q13.32
Functionis an important component in the neurobiology of neurodegenerative diseases.
PathwaysEpigenetic, Immune Response, Nf-Κb, Pi3K/Akt, Toll-Like Receptor
UniProt IDP53539
NCBI Gene ID2354
Ensembl IDENSG00000125740
OMIM164772
GeneCardsFOSB
Human Protein AtlasFOSB
Associated Diseasesneurodegeneration
InteractionsCX3CR1, APP, BDNF, EGR4, SOCS1, EGR1
KG Connections104 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Prefrontal sensory gating circuit restoration via PV interne
Score: 0.59
Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.50
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Optogenetic Microglial Deactivation via Engineered Inhibitor
Score: 0.38

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Packard Center for ALS Research
institution · KG edge: activates
Alzheimer Indonesia
institution · KG edge: inhibits
APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: inhibits
FOS Gene
gene · KG edge: activates
ERBB4 Gene
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

FOSB activates CX3CR1
FOSB inhibits APP
FOSB activates BDNF
FOSB activates EGR4
FOSB inhibits SOCS1
FOSB inhibits EGR1
FOSB inhibits Rb
FOSB expressed_in CAMK2G
FOSB associated_with EGR1
FOSB expressed_in CEBPA