gene 1,026 words KG: IGF2 2026-03-24
kind:genesection:genesstate:published
Contents

IGF2 (Insulin-Like Growth Factor 2)

🧬 Gene Info
Gene SymbolIGF2
AliasesInsulin-Like Growth Factor 2
FunctionIGF2 serves multiple physiological functions
Molecular Weight7.5 kDa
Amino Acids24 aa
PathwaysBlood-Brain Barrier
UniProt ID[P01344](https://www.uniprot.org/uniprot/P01344)
NCBI Gene ID3481
GeneCardsIGF2
Human Protein AtlasIGF2
Associated DiseasesALS, ALZHEIMER'S DISEASE, Alzheimer
InteractionsPIK3CA, AKT, NEURODEGENERATIVE DISEASES, ALS, AGING, NEURON
KG Connections191 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (10)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
SASP-Mediated Complement Cascade Amplification
Score: 0.70
APOE-Dependent Autophagy Restoration
Score: 0.61
Stress Granule Phase Separation Modulators
Score: 0.49
Lysosomal Enzyme Trafficking Correction
Score: 0.49

Related Analyses (8)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (9)

Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: activates
Packard Center for ALS Research
institution · KG edge: activates
Alzheimer Indonesia
institution · KG edge: associated_with
DYNC1I1 — Cytoplasmic Dynein 1 Intermediate Chain 1
gene · KG edge: expressed_in
BCL2 Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

IGF2 regulates IGF2R
IGF2 treats IGF2R
IGF2 expressed_in IGF2R
IGF2 expressed_in JUN
IGF2 regulates RB1
IGF2 regulates RB1CC1
IGF2 inhibits PIK3CA
IGF2 inhibits AKT
IGF2 regulates Cell Growth
IGF2 regulates Memory