Contents

NME1 - NME Nucleoside Diphosphate Kinase 1

🧬 Gene Info

Gene Symbol	NME1
Full Name	NME/Nucleoside Diphosphate Kinase 1
Aliases	Page for NME1 Protein
Chromosome	17q21.33
Protein Type	Enzyme
Function	is a ubiquitous enzyme that catalyzes the transfer of phosphate groups between nucleoside diphosphates (NDPs) and nucleoside triphosphates (NTPs).
Primary Expression	most human tissues:
Molecular Weight	17 kDa
Amino Acids	152 aa
UniProt ID	[P15531](https://www.uniprot.org/uniprot/P15531)
Ensembl ID	ENSG00000214021
GeneCards	NME1
Human Protein Atlas	NME1
N-terminal domain	Contains the phosphate-binding loop (P-loop) motif essential for nucleotide binding
Active site	His-118 serves as the central histidine residue mediating phosphate transfer
Associated Diseases	Als, Leukemia, Ms
Interactions	ASH1L, CAV1, RELN
KG Connections	41 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Knowledge Graph