gene 764 words KG: SLC17A5 2026-03-21
kind:genesection:genesstate:published
Contents

SLC17A5 Gene

🧬 Gene Info
Gene SymbolSLC17A5
Full NameSolute Carrier Family 17 Member 5 (Sialin)
Chromosome6q13
Functionis an important component in the neurobiology of neurodegenerative diseases.
Amino Acids495 aa
Exons14
PathwaysAlpha-Synuclein, Cholesterol
UniProt ID[Q9NRX3](https://www.uniprot.org/uniprot/Q9NRX3)
Ensembl IDENSG00000183040
GeneCardsSLC17A5
Human Protein AtlasSLC17A5
Exon count14 exons spanning approximately 25 kb
Promoter regionContains regulatory elements for tissue-specific expression
Coding sequenceEncodes a polytopic membrane protein with 10-12 transmembrane domains
Lysosomal exportExports sialic acid from lysosomes using the proton gradient as energy source[@sialin2019]
Associated DiseasesALS, Aging, Ms, Parkinson
InteractionsGNPTAB, SMPD1, NPC1, GBA, CTSD, LIPA
KG Connections70 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph