gene 1,640 words KG: TRPM3 2026-03-24
kind:genesection:genesstate:published
Contents

TRPM3 Gene - Transient Receptor Potential Channel

🧬 Gene Info
Gene SymbolTRPM3
AliasesPage for TRPM3 Gene
Chromosome9q21.11
Protein FamilyTRPM (Transient Receptor Potential Melastatin)
Protein TypeChannel
Functionencodes a calcium-permeable nonselective cation channel belonging to the TRPM (Transient Receptor Potential Melastatin) family.
Primary Expressionthe central nervous system, with particularly high expression in regions involved in temperature sensation and endocrine function
Molecular Weight168 kDa
PathwaysAkt
UniProt IDQ9BQY4
NCBI Gene ID80084
Ensembl IDENSG00000083099
OMIM608394
GeneCardsTRPM3
Human Protein AtlasTRPM3
Associated Diseasesneurodegeneration
InteractionsTRPA1, SRC
KG Connections9 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (7)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.62
Mechanosensitive Ion Channel Reprogramming
Score: 0.51
Lysosomal Calcium Channel Modulation Therapy
Score: 0.49
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.47

Related Analyses (10)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed

See Also (6)

TRPA1 Gene
gene · KG edge: inhibits
SRC Gene
gene · KG edge: inhibits
SCN8A Gene - Nav1.6
gene · KG edge: regulates
CREBBP Gene
gene · KG edge: regulates
AKT1 Gene
gene · KG edge: regulates

Knowledge Graph (9 edges)

TRPM3 regulates CREBBP
TRPM3 inhibits Ms
TRPM3 inhibits Migraine
TRPM3 regulates Akt
TRPA1 inhibits TRPM3
SRC inhibits TRPM3
SCN8A regulates TRPM3
AKT1 regulates TRPM3
TRPM2 implicated_in TRPM3