gene 2,948 words KG: VGLUT2 2026-03-27
kind:genesection:genestopic:parkinsonstopic:alzheimerstopic:alsstate:published
Contents

VGLUT2 Gene

🧬 Gene Info
Gene SymbolVGLUT2
Full NameVGLUT2
AliasesVesicular Glutamate Transporter 2
Chromosome19q13.43
Protein TypeGene
FunctionIts function encompasses several critical processes
Primary Expressionhypothalamic nuclei controlling autonomic and endocrine functions - Cortex: Limited to deep layers (V-VI) and specific interneuron populations -
Molecular Weight65 kDa
Amino Acids582 aa
PathwaysEpigenetic, Synaptic Plasticity, Synaptic Vesicle
NCBI Gene IDSearch NCBI
GeneCardsVGLUT2
Human Protein AtlasVGLUT2
Associated DiseasesISCHEMIA, epilepsy, neurodegeneration
InteractionsSLC17A7, SLC17A6, TAU, AND, PARKINSON'S DISEASE, EPILEPSY
KG Connections56 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Microbial Inflammasome Priming Prevention
Score: 0.58
SASP-Mediated Cholinergic Synapse Disruption
Score: 0.56
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.52
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (4)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (13)

Tau Consortium
organization · KG edge: activates
Packard Center for ALS Research
institution · KG edge: inhibits
vglut1
gene · KG edge: associated_with
slc17a7 Gene
gene · KG edge: activates
SLC17A6 Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

VGLUT2 associated_with VGLUT1
VGLUT2 expressed_in Dentate Gyrus
VGLUT2 activates SLC17A7
VGLUT2 expressed_in KDM6B
VGLUT2 expressed_in VGLUT1
VGLUT2 activates SLC17A6
VGLUT2 activates TAU
VGLUT2 activates Synaptic Vesicle
VGLUT2 associated_with epilepsy
VGLUT2 associated_with neurodegeneration