| Gene Symbol | WFS1 |
| Full Name | Wolframin ER Calcium Channel |
| Aliases | Page for WFS1 Protein |
| Chromosome | 4p16.1 |
| Function | The WFS1 gene encodes wolframin, a transmembrane protein localized primarily to the endoplasmic reticulum (ER). |
| Primary Expression | Pancreas, Brain, Heart, Kidney, Eye |
| Molecular Weight | 100.3 kDa |
| Amino Acids | 890 aa |
| Pathways | signaling:
- Activates Akt pathway |
| UniProt ID | O76024 |
| NCBI Gene ID | 7466 |
| Ensembl ID | ENSG00000109501 |
| OMIM | 222300 |
| GeneCards | WFS1 |
| Human Protein Atlas | WFS1 |
| Associated Diseases | Ataxia, Ms |
| Interactions | SRPK1 |
| KG Connections | 38 knowledge graph edges |
| Databases | GeneCardsHPASTRING |