gene 759 words KG: TWNK 2026-03-21
kind:genesection:genesstate:published
Contents

TWNK Gene

🧬 Gene Info
Gene SymbolTWNK
AliasesPEO1
Chromosome10q24.31
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight77 kDa
Amino Acids684 aa
UniProt IDQ96QR1
Ensembl IDENSG00000107815
OMIM604367
GeneCardsTWNK
Human Protein AtlasTWNK
Gene NameTwinkle Mitochondrial DNA Helicase
Also Known AsPEO1, TWNK
Associated DiseasesAtaxia, Ms
KG Connections41 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (4)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.47
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
R-Loop Resolution Enhancement Therapy
Score: 0.43

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

WFS1 — Wolfram Syndrome 1
gene · KG edge: associated_with
STUB1 — CHIP
gene · KG edge: associated_with
SLC25A4 Gene
gene · KG edge: associated_with
SIL1 Gene
gene · KG edge: associated_with
SETX Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

TWNK associated_with PNPLA6
TWNK associated_with MPV17
TWNK associated_with DGUOK
TWNK associated_with LARS2
TWNK associated_with SIL1
TWNK associated_with HARS
TWNK associated_with STUB1
TWNK associated_with WFS1
TWNK associated_with SETX
TWNK associated_with FMR1