| Gene Symbol | HDAC4 |
| Full Name | Histone Deacetylase 4 |
| Chromosome | 2q37.3 |
| Protein Family | Histone deacetylase, Class IIa |
| Function | Histone Modification: Removes acetyl groups from lysine tails of histones H3 and H4 |
| Subcellular Localization | </strong></td><td>Nucleus/Cytoplasm (signal-dependent shuttling)</td></tr> |
| Molecular Weight | 119 kDa |
| Amino Acids | 1088 aa |
| Pathways | NF-κB, AMPK |
| UniProt ID | [P56524](https://www.uniprot.org/uniprot/P56524) |
| Ensembl ID | ENSG00000113048 |
| OMIM | 605314 |
| GeneCards | HDAC4 |
| Human Protein Atlas | HDAC4 |
| MEF2-binding domain | HDAC4 represses MEF2 (Myocyte Enhancer Factor 2) transcription factors |
| Associated Diseases | Aging, ALS, Alzheimer, dementia, Soft Tissue Sarcoma, Tumor |
| Interactions | AGING, AMPK, AND, App, AQP1, CAMKII |
| KG Connections | 178 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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