| Gene Symbol | HDAC7 |
| Chromosome | 12q13 |
| Protein Type | Gene |
| Function | is a Class IIa histone deacetylase that plays crucial roles in gene regulation, cellular signaling, and neuronal function. |
| Molecular Weight | 103 kDa |
| Amino Acids | 669 aa |
| Pathways | Oxidative Stress |
| GeneCards | HDAC7 |
| Human Protein Atlas | HDAC7 |
| Epigenetic state control | HDAC7 participates in chromatin programs that can alter neuronal stress responses. |
| Cell-state coupling | class IIa HDACs shuttle between nucleus and cytoplasm in response to kinase signaling, linking activity state to gene expression programs. |
| Therapeutic tractability | the broader HDAC inhibitor field is clinically advanced, making HDAC7-containing complexes an attractive precision-targeting problem. |
| Associated Diseases | ALS, Cell Transformation, Tumor |
| Interactions | AKT, ALS, AMPK, AND, ATM, AXIN1 |
| KG Connections | 135 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!